Matthias P Lutolf
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Explore the profile of Matthias P Lutolf including associated specialties, affiliations and a list of published articles.
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138
Citations
8291
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Recent Articles
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2.
Hofer M, Duque-Correa M, Lutolf M
Nat Biomed Eng
. 2024 Dec;
PMID: 39633029
Organoids for modelling the physiology and pathology of gastrointestinal tissues are constrained by a poorly accessible lumen. Here we report the development and applicability of bilaterally accessible organoid-derived patterned epithelial...
3.
Lutolf M, Radisic M, Beekman J, Huh D, Huch M, Turco M, et al.
Trends Biotechnol
. 2024 Nov;
42(12):1577-1582.
PMID: 39490223
No abstract available.
4.
Lutolf M, Radisic M, Beekman J, Huh D, Huch M, Turco M, et al.
Cell
. 2024 Aug;
187(17):4439-4443.
PMID: 39178827
It is said that all models are wrong, but some are useful. In vitro human cell-based models are a prime example of this maxim. We asked researchers: when is your...
5.
Dutta D, Lorenzo-Martin L, Rivest F, Broguiere N, Tillard L, Ragusa S, et al.
NPJ Precis Oncol
. 2024 Aug;
8(1):179.
PMID: 39143103
Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models...
6.
Hubscher T, Lorenzo-Martin L, Barthlott T, Tillard L, Langer J, Rouse P, et al.
Development
. 2024 Jul;
151(17).
PMID: 39036995
Although the advent of organoids has opened unprecedented perspectives for basic and translational research, immune system-related organoids remain largely underdeveloped. Here, we established organoids from the thymus, the lymphoid organ...
7.
Lorenzo-Martin L, Broguiere N, Langer J, Tillard L, Nikolaev M, Coukos G, et al.
Nat Biotechnol
. 2024 Jul;
PMID: 38956326
Existing organoid models fall short of fully capturing the complexity of cancer because they lack sufficient multicellular diversity, tissue-level organization, biological durability and experimental flexibility. Thus, many multifactorial cancer processes,...
8.
Liu Y, Ansaryan S, Tan J, Broguiere N, Lorenzo-Martin L, Homicsko K, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(34):e2401539.
PMID: 38924371
Organoid tumor models have emerged as a powerful tool in the fields of biology and medicine as such 3D structures grown from tumor cells recapitulate better tumor characteristics, making these...
9.
Mitrofanova O, Nikolaev M, Xu Q, Broguiere N, Cubela I, Camp J, et al.
Cell Stem Cell
. 2024 Jun;
31(8):1175-1186.e7.
PMID: 38876106
Organoids and organs-on-a-chip have emerged as powerful tools for modeling human gut physiology and disease in vitro. Although physiologically relevant, these systems often lack the environmental milieu, spatial organization, cell...
10.
Lorenzo-Martin L, Lutolf M
Nat Rev Genet
. 2024 Jun;
25(9):598.
PMID: 38839917
No abstract available.