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Nicolas Broguiere

Explore the profile of Nicolas Broguiere including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 960
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Recent Articles
11.
Berg I, Rizzo R, Lee M, Ren Q, Broguiere N, Zenobi-Wong M
ACS Biomater Sci Eng . 2021 May; 7(6):2198-2203. PMID: 34043314
Biomedical adhesives have been found to be an attractive alternative to suturing in several circumstances. However, to date most of the clinically approved formulations are based on synthetic and highly...
12.
Girgin M, Broguiere N, Mattolini L, Lutolf M
Stem Cell Reports . 2021 Apr; 16(5):1143-1155. PMID: 33891872
When stimulated with a pulse from an exogenous WNT pathway activator, small aggregates of mouse embryonic stem cells (ESCs) can undergo embryo-like axial morphogenesis and patterning along the three major...
13.
Broguiere N, Cavalli E, Salzmann G, Applegate L, Zenobi-Wong M
ACS Biomater Sci Eng . 2021 Jan; 2(12):2176-2184. PMID: 33465893
In this study, transglutaminase-cross-linked hyaluronan (HA-TG) hydrogels are investigated for their potential to treat cartilage lesions. We show the hydrogels fulfill key requirements: they are simultaneously injectable, fast-gelling, biocompatible with...
14.
Mazunin D, Broguiere N, Zenobi-Wong M, Bode J
ACS Biomater Sci Eng . 2021 Jan; 1(6):456-462. PMID: 33445248
The synthesis of novel PEG-based hydrogel via chemoselective potassium acyl trifluoroborate (KAT) and -carbamoyl hydroxylamines amide ligation is reported. The gelation kinetics, determined by dynamic rheometry, is pH dependent and...
15.
Rossi G, Broguiere N, Miyamoto M, Boni A, Guiet R, Girgin M, et al.
Cell Stem Cell . 2020 Nov; 28(2):230-240.e6. PMID: 33176168
Organoids are powerful models for studying tissue development, physiology, and disease. However, current culture systems disrupt the inductive tissue-tissue interactions needed for the complex morphogenetic processes of native organogenesis. Here,...
16.
Nikolaev M, Mitrofanova O, Broguiere N, Geraldo S, Dutta D, Tabata Y, et al.
Nature . 2020 Sep; 585(7826):574-578. PMID: 32939089
Epithelial organoids, such as those derived from stem cells of the intestine, have great potential for modelling tissue and disease biology. However, the approaches that are used at present to...
17.
Santos T, Schaffran B, Broguiere N, Meyn L, Zenobi-Wong M, Bradke F
Cell Rep . 2020 Jul; 32(3):107907. PMID: 32698008
During development of the central nervous system (CNS), neurons polarize and rapidly extend their axons to assemble neuronal circuits. The growth cone leads the axon to its target and drives...
18.
Broguiere N, Luchtefeld I, Trachsel L, Mazunin D, Rizzo R, Bode J, et al.
Adv Mater . 2020 May; 32(25):e1908299. PMID: 32390195
Three-dimensional (3D) control over the placement of bioactive cues is fundamental to understand cell guidance and develop engineered tissues. Two-photon patterning (2PP) provides such placement at micro- to millimeter scale,...
19.
Trachsel L, Broguiere N, Rosenboom J, Zenobi-Wong M, Benetti E
J Mater Chem B . 2020 Apr; 6(46):7568-7572. PMID: 32254878
Molecularly designed, random copolymer-bioconjugates based on poly(2-methyl-2-oxazoline) (PMOXA) and poly(2-ethyl-2-oxazoline) (PEOXA) are crosslinked in the presence of sortase A (SA) and human articular chondrocytes (hACs), to yield cellularized polymer networks....
20.
Cavalli E, Levinson C, Hertl M, Broguiere N, Bruck O, Mustjoki S, et al.
Sci Rep . 2019 Mar; 9(1):4275. PMID: 30862915
Treating cartilage injuries and degenerations represents an open surgical challenge. The recent advances in cell therapies have raised the need for a potent off-the-shelf cell source. Intra-articular injections of TGF-β...