Nicola Pozzi
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Explore the profile of Nicola Pozzi including associated specialties, affiliations and a list of published articles.
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77
Citations
908
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Recent Articles
1.
Ren Z, Bao J, Zhao S, Pozzi N, Wedner H, Wedner H, et al.
JCI Insight
. 2025 Jan;
10(4).
PMID: 39823539
Hereditary angioedema is an autosomal dominant disorder caused by defects in C1-esterase inhibitor (C1-INH), resulting in poorly controlled activation of the kallikrein-kinin system and bradykinin overproduction. C1-INH is a heavily...
2.
Kyriukha Y, Watkins M, Redington J, Chintalapati N, Ganti A, Dastvan R, et al.
iScience
. 2024 Nov;
27(12):111259.
PMID: 39584160
The partner and localizer of BRCA2 (PALB2) is a scaffold protein linking BRCA1 with BRCA2 and RAD51 during homologous recombination (HR). PALB2 interaction with DNA strongly enhances HR in cells,...
3.
Ponzar N, Chinnaraj M, Pagotto A, De Filippis V, Flaumenhaft R, Pozzi N
J Thromb Haemost
. 2024 Oct;
23(2):577-587.
PMID: 39454880
Background: Protein disulfide isomerase (PDI) is a promising target for combating thrombosis. Extensive research over the past decade has identified numerous PDI-targeting compounds. However, limited information exists regarding how these...
4.
Ward C, Curry N, El-Ekiaby M, Jurk K, Versteeg H, Keragala C, et al.
Res Pract Thromb Haemost
. 2024 Sep;
8(5):102498.
PMID: 39268352
[This corrects the article DOI: 10.1016/j.rpth.2024.102432.].
5.
Hasdemir H, Pozzi N, Tajkhorshid E
J Thromb Haemost
. 2024 Jul;
22(11):3277-3289.
PMID: 39047943
Background: Interaction of β-glycoprotein I (βGPI) with anionic membranes is crucial in antiphospholipid syndrome (APS), implicating the role of its membrane-binding domain, domain V (DV). The mechanism of DV binding...
6.
Pozzi N, Pontara E, Kumar S, Pengo V
J Thromb Haemost
. 2024 Jul;
22(10):2935-2938.
PMID: 39029741
No abstract available.
7.
Ward C, Curry N, El-Ekiaby M, Jurk K, Versteeg H, Keragala C, et al.
Res Pract Thromb Haemost
. 2024 Jun;
8(4):102432.
PMID: 38854821
Here, we present a series of illustrated capsules from the State of the Art (SOA) speakers at the 2024 International Society on Thrombosis and Haemostasis Congress in Bangkok, Thailand. This...
8.
Hasdemir H, Pozzi N, Tajkhorshid E
bioRxiv
. 2024 Apr;
PMID: 38562685
Background: Interaction of beta-2-glycoprotein I ( GPI) with anionic membranes is crucial in antiphospholipid syndrome (APS), implicating the role of it's membrane bind-ing domain, Domain V (DV). The mechanism of...
9.
Kumar S, Summers B, Basore K, Pengo V, Flaumenhaft R, Pozzi N
Blood
. 2024 Mar;
143(19):2005-2011.
PMID: 38437497
Antiprothrombin antibodies are found in antiphospholipid patients, but how they interact with prothrombin remains elusive. Prothrombin adopts closed and open forms. We recently discovered type I and type II antibodies...
10.
Acquasaliente L, Pierangelini A, Pagotto A, Pozzi N, De Filippis V
Protein Sci
. 2023 Nov;
32(12):e4825.
PMID: 37924304
Hirudin from Hirudo medicinalis is a bivalent α-Thrombin (αT) inhibitor, targeting the enzyme active site and exosite-I, and is currently used in anticoagulant therapy along with its simplified analogue hirulog....