Robert Flaumenhaft
Overview
Explore the profile of Robert Flaumenhaft including associated specialties, affiliations and a list of published articles.
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124
Citations
3149
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Recent Articles
1.
Ummarino S, Poluben L, Ebralidze A, Autiero I, Ebralidze A, Zhang Y, et al.
Res Sq
. 2025 Feb;
PMID: 39975922
Coordinated initiation of DNA replication is essential to ensure efficient and timely DNA synthesis. Yet, molecular mechanism describing how replication initiation is coordinated in eukaryotic cells is not completely understood....
2.
Jiang L, Yuan C, Flaumenhaft R, Huang M
Thromb J
. 2025 Feb;
23(1):16.
PMID: 39962537
Vascular thiol isomerases (VTIs) encompass proteins such as protein disulfide isomerase (PDI), endoplasmic reticulum protein 5 (ERp5), ERp46, ERp57, ERp72, thioredoxin-related transmembrane protein 1 (TMX1), and TMX4, and play pivotal...
3.
Yang M, Hancco Zirena I, Kennedy Q, Patel A, Merrill-Skoloff G, Sack K, et al.
J Thromb Haemost
. 2025 Feb;
PMID: 39952360
Background: Both protein disulfide isomerase (PDI) and SARS-CoV-2 main protease (M) are reliant on active-site cysteines stabilized by adjacent amino acids. We reasoned that redox-active compounds might interfere with both...
4.
Wang R, Li H, Xie Z, Huang M, Xu P, Yuan C, et al.
Sci Adv
. 2025 Jan;
11(3):eads1796.
PMID: 39813336
The angiopoietin (Ang)-Tie axis, critical for endothelial cell function and vascular development, is a promising therapeutic target for treating vascular disorders and inflammatory conditions like sepsis. This study aimed to...
5.
Woronowicz K, Flaumenhaft R
Methods Mol Biol
. 2025 Jan;
2887():135-147.
PMID: 39806151
The actin cytoskeleton serves an important, but poorly characterized, role in controlling granule exocytosis. The dynamic nature of actin remodeling allows it to act both as a barrier to prevent...
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Ponzar N, Chinnaraj M, Pagotto A, De Filippis V, Flaumenhaft R, Pozzi N
J Thromb Haemost
. 2024 Oct;
23(2):577-587.
PMID: 39454880
Background: Protein disulfide isomerase (PDI) is a promising target for combating thrombosis. Extensive research over the past decade has identified numerous PDI-targeting compounds. However, limited information exists regarding how these...
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Marquez J, Simon S, Zwicker J, Flaumenhaft R, Hollenbeck B, Patell R
Leuk Res
. 2024 Sep;
146:107591.
PMID: 39332262
No abstract available.