Nickolay V Kukekov
Overview
Explore the profile of Nickolay V Kukekov including associated specialties, affiliations and a list of published articles.
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7
Citations
145
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Recent Articles
1.
Rajan R, Krutilina R, Ignatova T, Pavicevich Z, Dulatova G, Lane M, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298091
Adaptive plasticity of Breast Cancer stem cells (BCSCs) is strongly correlated with cancer progression and resistance, leading to a poor prognosis. In this study, we report the expression profile of...
2.
Ignatova T, Chaitin H, Kukekov N, Suslov O, Dulatova G, Hanafy K, et al.
J Neurosurg Sci
. 2021 Aug;
68(2):148-156.
PMID: 34342203
Background: Glioblastoma multiforme (GBM) is a lethal brain tumor characterized by developmental hierarchical phenotypic heterogeneity, therapy resistance and recurrent growth. Neural stem cells (NSCs) from human central nervous system (CNS),...
3.
Wilhelm M, Kukekov N, Schmit T, Biagas K, Sproul A, Gire S, et al.
J Biol Chem
. 2011 Dec;
287(3):2247-56.
PMID: 22128169
We report that Sh3rf2, a homologue of the pro-apoptotic scaffold POSH (Plenty of SH3s), acts as an anti-apoptotic regulator for the c-Jun N-terminal kinase (JNK) pathway. siRNA-mediated knockdown of Sh3rf2...
4.
Wilhelm M, Kukekov N, Xu Z, Greene L
Dev Neurosci
. 2007 Sep;
29(4-5):355-62.
PMID: 17762203
The c-Jun N-terminal kinase (JNK) pathway plays an important role in neuronal apoptosis both during normal CNS development and following stroke in adult animals. As with other MAP kinase pathways,...
5.
Wilhelm M, Xu Z, Kukekov N, Gire S, Greene L
J Biol Chem
. 2006 Nov;
282(2):1288-95.
PMID: 17095503
Nix, a pro-apoptotic BH3-only protein, promotes apoptosis of non-neuronal cells, although the mechanisms involved remain incompletely understood. Using a yeast two-hybrid screen with POSH (plenty of SH3 domains, a scaffold...
6.
Kukekov N, Xu Z, Greene L
J Biol Chem
. 2006 Mar;
281(22):15517-24.
PMID: 16571722
A sequential pathway (the JNK pathway) that includes activation of Rac1/Cdc42, mixed lineage kinases, MAP kinase kinases 4 and 7, and JNKs plays a required role in many paradigms of...
7.
Xu Z, Kukekov N, Greene L
EMBO J
. 2003 Jan;
22(2):252-61.
PMID: 12514131
We report that the multidomain protein POSH (plenty of SH3s) acts as a scaffold for the JNK pathway of neuronal death. This pathway consists of a sequential cascade involving activated...