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Tatyana N Ignatova

Explore the profile of Tatyana N Ignatova including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 923
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Recent Articles
1.
Rajan R, Krutilina R, Ignatova T, Pavicevich Z, Dulatova G, Lane M, et al.
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298091
Adaptive plasticity of Breast Cancer stem cells (BCSCs) is strongly correlated with cancer progression and resistance, leading to a poor prognosis. In this study, we report the expression profile of...
2.
Ignatova T, Chaitin H, Kukekov N, Suslov O, Dulatova G, Hanafy K, et al.
J Neurosurg Sci . 2021 Aug; 68(2):148-156. PMID: 34342203
Background: Glioblastoma multiforme (GBM) is a lethal brain tumor characterized by developmental hierarchical phenotypic heterogeneity, therapy resistance and recurrent growth. Neural stem cells (NSCs) from human central nervous system (CNS),...
3.
Gibbs C, Kukekov V, Reith J, Tchigrinova O, Suslov O, Scott E, et al.
Neoplasia . 2005 Dec; 7(11):967-76. PMID: 16331882
Bone sarcomas are a clinically and molecularly heterogeneous group of malignancies characterized by varying degrees of mesenchymal differentiation. Despite advances in medical and surgical management, survival rates for high-grade tumors...
4.
Mason J, Angelastro J, Ignatova T, Kukekov V, Lin G, Greene L, et al.
Mol Cell Neurosci . 2005 Jun; 29(3):372-80. PMID: 15950153
The transcription factor ATF5 is expressed in cells of the embryonic and neonatal ventricular zone/subventricular zone (VZ/SVZ), and must be down-regulated for their differentiation into neurons and astrocytes. Here, we...
5.
Angelastro J, Mason J, Ignatova T, Kukekov V, Stengren G, Goldman J, et al.
J Neurosci . 2005 Apr; 25(15):3889-99. PMID: 15829641
The mechanisms that regulate neural progenitor cell differentiation are primarily unknown. The transcription factor activating transcription factor 5 (ATF5) is expressed in neural progenitors of developing brain but is absent...
6.
Svetlov S, Ignatova T, Wang K, Hayes R, English D, Kukekov V
Stem Cells Dev . 2005 Feb; 13(6):685-93. PMID: 15684836
Neural stem/progenitor cells are clonogenic in vitro and produce neurospheres in serum-free medium containing epidermal growth factor (EGF) and fibroblast growth factor (FGF2). Here, we demonstrate that lysophosphatidic acid (LPA)...
7.
Melixetian M, Pavlenko M, Beriozkina E, Kovaleva Z, Sorokina E, Ignatova T, et al.
Hybrid Hybridomics . 2003 Dec; 22(5):321-7. PMID: 14678650
The use of multidrug-resistant variant of Sp2/0 mouse myeloma cell line SpEBr-5 as a partner for making mouse hybridoma producing monoclonal antibodies is described here. The resulting hybridoma cell line...
8.
Angelastro J, Ignatova T, Kukekov V, Steindler D, Stengren G, Mendelsohn C, et al.
J Neurosci . 2003 Jun; 23(11):4590-600. PMID: 12805299
An important milestone in brain development is the transition of neuroprogenitor cells to postmitotic neurons. We report that the bZIP transcription factor ATF5 plays a major regulatory role in this...
9.
Suslov O, Kukekov V, Ignatova T, Steindler D
Proc Natl Acad Sci U S A . 2002 Oct; 99(22):14506-11. PMID: 12381788
Neural stem cells (NSCs) in vitro are able to generate clonal structures, "neurospheres," that exhibit intra-clonal neural cell-lineage diversity; i.e., they contain, in addition to NSCs, neuronal and glial progenitors...
10.
Ignatova T, Kukekov V, Laywell E, Suslov O, Vrionis F, Steindler D
Glia . 2002 Aug; 39(3):193-206. PMID: 12203386
Neural stem cells from neurogenic regions of mammalian CNS are clonogenic in an in vitro culture system exploiting serum and anchorage withdrawal in medium supplemented with methyl cellulose and the...