Nicklas Bonander
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Explore the profile of Nicklas Bonander including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Cartwright S, Darby R, Sarkar D, Bonander N, Gross S, Ashe M, et al.
Microb Cell Fact
. 2017 Mar;
16(1):41.
PMID: 28279185
Background: We previously selected four strains of Saccharomyces cerevisiae for their ability to produce the aquaporin Fps1 in sufficient yield for further study. Yields from the yeast strains spt3Δ, srb5Δ,...
2.
Westman J, Bonander N, Taherzadeh M, Franzen C
Biotechnol Biofuels
. 2014 Jul;
7:102.
PMID: 25050138
Background: Two major hurdles for successful production of second-generation bioethanol are the presence of inhibitory compounds in lignocellulosic media, and the fact that Saccharomyces cerevisiae cannot naturally utilise pentoses. There...
3.
Bonander N, Jamshad M, Oberthur D, Clare M, Barwell J, Hu K, et al.
PLoS One
. 2013 May;
8(5):e64517.
PMID: 23704991
The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1, also associates with tetraspanin CD81 as part of a...
4.
Bonander N, Bill R
Methods Mol Biol
. 2012 Mar;
866:1-9.
PMID: 22454109
Having access to suitably stable, functional recombinant protein samples underpins diverse academic and industrial research efforts to understand the workings of the cell in health and disease. Synthesising a protein...
5.
Bawa Z, Bland C, Bonander N, Bora N, Cartwright S, Clare M, et al.
Biochem Soc Trans
. 2011 May;
39(3):719-23.
PMID: 21599640
Membrane proteins are drug targets for a wide range of diseases. Having access to appropriate samples for further research underpins the pharmaceutical industry's strategy for developing new drugs. This is...
6.
Bonander N, Jamshad M, Hu K, Farquhar M, Stamataki Z, Balfe P, et al.
Biochem Soc Trans
. 2011 Mar;
39(2):537-40.
PMID: 21428935
Tetraspanins are thought to exert their biological function(s) by co-ordinating the lateral movement and trafficking of associated molecules into tetraspanin-enriched microdomains. A second four-TM (transmembrane) domain protein family, the Claudin...
7.
Ferndahl C, Bonander N, Logez C, Wagner R, Gustafsson L, Larsson C, et al.
Microb Cell Fact
. 2010 Jun;
9:47.
PMID: 20565740
Background: Recombinant protein production is universally employed as a solution to obtain the milligram to gram quantities of a given protein required for applications as diverse as structural genomics and...
8.
Bonander N, Bill R
Expert Rev Proteomics
. 2009 Oct;
6(5):501-5.
PMID: 19811071
The slow down in the drug discovery pipeline is, in part, owing to a lack of structural and functional information available for new drug targets. Membrane proteins, the targets of...
9.
Bonander N, Darby R, Grgic L, Bora N, Wen J, Brogna S, et al.
Microb Cell Fact
. 2009 Jan;
8:10.
PMID: 19178690
Background: The production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a truly rational manner. Typically eukaryotic...
10.
Bonander N, Ferndahl C, Mostad P, Wilks M, Chang C, Showe L, et al.
BMC Genomics
. 2008 Aug;
9:365.
PMID: 18671860
Background: We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently...