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Nick Goldman

Explore the profile of Nick Goldman including associated specialties, affiliations and a list of published articles. Areas
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Articles 94
Citations 11414
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Recent Articles
1.
Bhandari B, Goldman N
NAR Genom Bioinform . 2024 Sep; 6(3):lqae126. PMID: 39296929
Protein sequencing is a rapidly evolving field with much progress towards the realization of a new generation of protein sequencers. The early devices, however, may not be able to reliably...
2.
Boulton W, Fidan F, Denise H, De Maio N, Goldman N
Bioinformatics . 2024 Sep; 40(9). PMID: 39226177
Motivation: Tracking SARS-CoV-2 variants through genomic sequencing has been an important part of the global response to the pandemic and remains a useful tool for surveillance of the virus. As...
3.
Cameron E, Sanchez S, Goldman N, Blaxter M, Finn R
Sci Rep . 2024 Aug; 14(1):18658. PMID: 39134591
Cyanobacteria are globally occurring photosynthetic bacteria notable for their contribution to primary production and production of toxins which have detrimental ecosystem impacts. Furthermore, cyanobacteria can form mutualistic symbiotic relationships with...
4.
Sauerborn E, Corredor N, Reska T, Perlas A, Vargas da Fonseca Atum S, Goldman N, et al.
Nat Commun . 2024 Jun; 15(1):5494. PMID: 38944650
Real-time genomics through nanopore sequencing holds the promise of fast antibiotic resistance prediction directly in the clinical setting. However, concerns about the accuracy of genomics-based resistance predictions persist, particularly when...
5.
Ghosh T, Almeida R, Zhao C, Mannioui A, Martin E, Fleet A, et al.
Cell . 2024 Feb; 187(4):814-830.e23. PMID: 38364788
Myelin, the insulating sheath that surrounds neuronal axons, is produced by oligodendrocytes in the central nervous system (CNS). This evolutionary innovation, which first appears in jawed vertebrates, enabled rapid transmission...
6.
Kapli P, Kotari I, Telford M, Goldman N, Yang Z
Syst Biol . 2023 Jun; 72(5):1119-1135. PMID: 37366056
Inference of deep phylogenies has almost exclusively used protein rather than DNA sequences based on the perception that protein sequences are less prone to homoplasy and saturation or to issues...
7.
De Maio N, Kalaghatgi P, Turakhia Y, Corbett-Detig R, Minh B, Goldman N
Nat Genet . 2023 Apr; 55(5):746-752. PMID: 37038003
Phylogenetics has a crucial role in genomic epidemiology. Enabled by unparalleled volumes of genome sequence data generated to study and help contain the COVID-19 pandemic, phylogenetic analyses of SARS-CoV-2 genomes...
8.
Weilguny L, De Maio N, Munro R, Manser C, Birney E, Loose M, et al.
Nat Biotechnol . 2023 Jan; 41(7):1018-1025. PMID: 36593407
Nanopore sequencers can select which DNA molecules to sequence, rejecting a molecule after analysis of a small initial part. Currently, selection is based on predetermined regions of interest that remain...
9.
Vohringer H, Sanderson T, Sinnott M, De Maio N, Nguyen T, Goater R, et al.
Nature . 2022 Jun; 606(7915):E18. PMID: 35701578
No abstract available.
10.
De Maio N, Boulton W, Weilguny L, Walker C, Turakhia Y, Corbett-Detig R, et al.
PLoS Comput Biol . 2022 Apr; 18(4):e1010056. PMID: 35486906
Sequence simulators are fundamental tools in bioinformatics, as they allow us to test data processing and inference tools, and are an essential component of some inference methods. The ongoing surge...