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Ari Loytynoja

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Articles 41
Citations 4706
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Recent Articles
1.
Tange Olsen M, Loytynoja A, Valtonen M, Knudsen S, Bang S, Gunnersen C, et al.
Ecol Evol . 2025 Mar; 15(3):e71067. PMID: 40040937
Spatiotemporal environmental heterogeneity is a major evolutionary driver, which can cause profound phylogeographic complexity, particularly at the periphery of species ranges. Ringed seals display a highly disjoint distribution, occurring in...
2.
Yi X, Wang D, Reid K, Feng X, Loytynoja A, Merila J
Evol Lett . 2024 Sep; 8(5):658-668. PMID: 39328282
Recent discoveries of sex chromosome diversity across the tree of life have challenged the canonical model of conserved sex chromosome evolution and evoked new theories on labile sex chromosomes that...
3.
Wang D, Rastas P, Yi X, Loytynoja A, Kivikoski M, Feng X, et al.
G3 (Bethesda) . 2024 Jun; 14(8). PMID: 38861393
The nine-spined stickleback (Pungitius pungitius) has been increasingly used as a model system in studies of local adaptation and sex chromosome evolution but its current reference genome assembly is far...
4.
Feng X, Merila J, Loytynoja A
Mol Biol Evol . 2024 Feb; 41(2). PMID: 38366566
Advances in genomic studies have revealed that hybridization in nature is pervasive and raised questions about the dynamics of different genetic and evolutionary factors following the initial hybridization event. While...
5.
Monttinen H, Frilander M, Loytynoja A
Proc Natl Acad Sci U S A . 2023 Nov; 120(49):e2310752120. PMID: 38019864
The mechanisms generating novel genes and genetic information are poorly known, even for microRNA (miRNA) genes with an extremely constrained design. All miRNA primary transcripts need to fold into a...
6.
Rosing-Asvid A, Loytynoja A, Momigliano P, Hansen R, Scharff-Olsen C, Valtonen M, et al.
Mol Ecol . 2023 Oct; 32(22):5932-5943. PMID: 37855154
The Earth's polar regions are low rates of inter- and intraspecific diversification. An extreme mammalian example is the Arctic ringed seal (Pusa hispida hispida), which is assumed to be panmictic...
7.
Olkkonen E, Loytynoja A
STAR Protoc . 2023 Sep; 4(4):102567. PMID: 37740912
This protocol demonstrates how a fragmented reference genome and low-coverage sequencing data can be efficiently utilized for population genetic analyses of a species with highly reduced genetic diversity. Focusing on...
8.
Loytynoja A, Rastas P, Valtonen M, Kammonen J, Holm L, Tange Olsen M, et al.
Curr Biol . 2023 Feb; 33(6):1009-1018.e7. PMID: 36822202
In the face of the human-caused biodiversity crisis, understanding the theoretical basis of conservation efforts of endangered species and populations has become increasingly important. According to population genetics theory, population...
9.
Kivikoski M, Rastas P, Loytynoja A, Merila J
Heredity (Edinb) . 2022 Dec; 130(3):114-121. PMID: 36566319
Map distance is one of the key measures in genetics and indicates the expected number of crossovers between two loci. Map distance is estimated from the observed recombination frequency using...
10.
Feng X, Merila J, Loytynoja A
Mol Ecol . 2022 Aug; 31(20):5386-5401. PMID: 35962788
Introgressive hybridization is an important process in evolution but challenging to identify, undermining the efforts to understand its role and significance. On the contrary, many analytical methods assume direct descent...