Nick D Read
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Explore the profile of Nick D Read including associated specialties, affiliations and a list of published articles.
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84
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4075
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Recent Articles
21.
Zhao C, Fernandez A, Avlonitis N, Velde G, Bradley M, Read N, et al.
ACS Comb Sci
. 2016 Oct;
18(11):689-696.
PMID: 27723293
With the advent of antimicrobial resistance, there is an urgent need for new strategies to treat infectious diseases. Antimicrobial peptides are considered as promising candidates, and therefore there is a...
22.
Weichert M, Lichius A, Priegnitz B, Brandt U, Gottschalk J, Nawrath T, et al.
Proc Natl Acad Sci U S A
. 2016 Oct;
113(42):11877-11882.
PMID: 27708165
Sterols are vital components of eukaryotic cell membranes. Defects in sterol biosynthesis, which result in the accumulation of precursor molecules, are commonly associated with cellular disorders and disease. However, the...
23.
Sintes M, de Moliner F, Caballero-Lima D, Denning D, Read N, Kielland N, et al.
Bioconjug Chem
. 2016 Jun;
27(6):1430-4.
PMID: 27248580
Herein we report the preparation of BODIPY mesoionic acid fluorides through a short sequence involving an isocyanide multicomponent reaction as the key synthetic step. These novel BODIPY acid fluorides are...
24.
Zhang Y, Zheng Q, Sun C, Song J, Gao L, Zhang S, et al.
PLoS Genet
. 2016 Apr;
12(4):e1005977.
PMID: 27058039
Finely tuned changes in cytosolic free calcium ([Ca2+]c) mediate numerous intracellular functions resulting in the activation or inactivation of a series of target proteins. Palmitoylation is a reversible post-translational modification...
25.
Mendive-Tapia L, Zhao C, Akram A, Preciado S, Albericio F, Lee M, et al.
Nat Commun
. 2016 Mar;
7:10940.
PMID: 26956772
Fluorescent antimicrobial peptides are promising structures for in situ, real-time imaging of fungal infection. Here we report a fluorogenic probe to image Aspergillus fumigatus directly in human pulmonary tissue. We...
26.
El-Mounadi K, Islam K, Hernandez-Ortiz P, Read N, Shah D
Mol Microbiol
. 2016 Jan;
100(3):542-59.
PMID: 26801962
Defensins play an important role in plant defense against fungal pathogens. The plant defensin, MtDef4, inhibits growth of the ascomycete fungi, Neurospora crassa and Fusarium graminearum, at micromolar concentrations. We...
27.
Munoz A, Bertuzzi M, Bettgenhaeuser J, Iakobachvili N, Bignell E, Read N
PLoS One
. 2015 Sep;
10(9):e0138008.
PMID: 26402916
Aspergillus fumigatus is an inhaled fungal pathogen of human lungs, the developmental growth of which is reliant upon Ca2+-mediated signalling. Ca2+ signalling has regulatory significance in all eukaryotic cells but...
28.
Bleichrodt R, Vinck A, Read N, Wosten H
Fungal Genet Biol
. 2015 Jul;
82:193-200.
PMID: 26212073
Hyphae of ascomycetes are compartmentalized by septa. The central pore in these septa allows for cytoplasmic streaming. However, many of these pores are closed by Woronin bodies in Aspergillus, which...
29.
Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns T, Munoz A, Walker L, et al.
PLoS Pathog
. 2015 Jun;
11(6):e1004943.
PMID: 26086393
No abstract available.
30.
Juvvadi P, Munoz A, Lamoth F, Soderblom E, Moseley M, Read N, et al.
Antimicrob Agents Chemother
. 2015 Jun;
59(8):4946-55.
PMID: 26055379
The echinocandin antifungal drug caspofungin at high concentrations reverses the growth inhibition of Aspergillus fumigatus, a phenomenon known as the "paradoxical effect," which is not consistently observed with other echinocandins...