Nick D Read
Overview
Explore the profile of Nick D Read including associated specialties, affiliations and a list of published articles.
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84
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4075
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Recent Articles
1.
Kurian S, Lichius A, Read N
J Fungi (Basel)
. 2022 Jan;
8(1).
PMID: 35050029
is an important plant pathogen and an emerging opportunistic human pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes (CATs) are significant events during colony establishment in...
2.
Ben-Ghazzi N, Moreno-Velasquez S, Seidel C, Thomson D, Denning D, Read N, et al.
J Fungi (Basel)
. 2021 Jul;
7(6).
PMID: 34200399
The precise characterization of the mechanisms modulating survival within airway epithelial cells has been impaired by the lack of live-cell imaging technologies and user-friendly quantification approaches. Here we described the...
3.
Munoz A, Bertuzzi M, Seidel C, Thomson D, Bignell E, Read N
Fungal Genet Biol
. 2020 Sep;
151:103470.
PMID: 32979514
Calcium signalling plays a fundamental role in fungal intracellular signalling. Previous approaches (fluorescent dyes, bioluminescent aequorin, genetically encoded cameleon probes) with imaging rapid subcellular changes in cytosolic free calcium ([Ca])...
4.
Seidel C, Moreno-Velasquez S, Ben-Ghazzi N, Gago S, Read N, Bowyer P
Front Microbiol
. 2020 Sep;
11:1955.
PMID: 32973709
is the most important mould pathogen in immunosuppressed patients. Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by invasive hyphae. The first point of contact...
5.
Alexander A, Munoz A, Marcos J, Read N
Mol Microbiol
. 2020 Sep;
114(4):521-535.
PMID: 32898933
Fungal diseases are responsible for the deaths of over 1.5 million people worldwide annually. Antifungal peptides represent a useful source of antifungals with novel mechanisms-of-action, and potentially provide new methods...
6.
Bleichrodt R, Foster P, Howell G, Latge J, Read N
mBio
. 2020 May;
11(3).
PMID: 32398317
can cause a variety of lung diseases in immunocompromised patients, including life-threatening invasive aspergillosis. There are only three main classes of antifungal drugs currently used to treat aspergillosis, and antifungal...
7.
du Pre S, Birch M, Law D, Beckmann N, Sibley G, Bromley M, et al.
J Fungi (Basel)
. 2020 Apr;
6(2).
PMID: 32290206
The first characterized antifungal in the orotomide class is olorofim. It targets the de novo pyrimidine biosynthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH). The pyrimidines uracil, thymine and cytosine are...
8.
Macdonald D, Thomson D, Johns A, Valenzuela A, Gilsenan J, Lord K, et al.
Antimicrob Agents Chemother
. 2019 May;
63(6).
PMID: 31126922
No abstract available.
9.
Medina-Castellanos E, Villalobos-Escobedo J, Riquelme M, Read N, Abreu-Goodger C, Herrera-Estrella A
PLoS Genet
. 2018 Dec;
14(11):e1007390.
PMID: 30500812
The ability to respond to injury is a biological process shared by organisms of different kingdoms that can even result in complete regeneration of a part or structure that was...
10.
Macdonald D, Thomson D, Johns A, Valenzuela A, Gilsenan J, Lord K, et al.
Antimicrob Agents Chemother
. 2018 Nov;
63(1).
PMID: 30397071
Antifungal agents directed against novel therapeutic targets are required for treating invasive, chronic, and allergic infections. Competitive fitness profiling technologies have been used in a number of bacterial and yeast...