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Nicholas Zavazava

Explore the profile of Nicholas Zavazava including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 476
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Recent Articles
1.
Li Y, Guan X, Liu W, Chen H, Truscott J, Beyatli S, et al.
J Immunol . 2018 Oct; 201(10):2910-2922. PMID: 30291167
Helminths stimulate the secretion of Th2 cytokines, like IL-4, and suppress lethal graft-versus-host disease (GVHD) after bone marrow transplantation. This suppression depends on the production of immune-modulatory TGF-β and is...
2.
Sweeney S, Manzar G, Zavazava N, Assouline J
Stem Cell Res Ther . 2018 Jul; 9(1):204. PMID: 30053892
Background: As the prevalence of therapeutic approaches involving transplanted cells increases, so does the need to noninvasively track the cells to determine their homing patterns. Of particular interest is the...
3.
Manzar G, Kim E, Zavazava N
J Biol Chem . 2017 Apr; 292(34):14066-14079. PMID: 28360105
Type 1 diabetes (T1D) can be managed by transplanting either the whole pancreas or isolated pancreatic islets. However, cadaveric pancreas is scarcely available for clinical use, limiting this approach. As...
4.
Kim E, Manzar G, Zavazava N
Immunology . 2017 Feb; 151(2):191-197. PMID: 28185259
The safety of induced pluripotent stem cells (iPSCs) in autologous recipients has been questioned after iPSCs, but not embryonic stem cells (ESCs), were reported to be rejected in syngeneic mice....
5.
Zavazava N
Transplantation . 2015 Oct; 99(11):2245-6. PMID: 26451526
No abstract available.
6.
Raikwar S, Kim E, Sivitz W, Allamargot C, Thedens D, Zavazava N
PLoS One . 2015 Jan; 10(1):e0116582. PMID: 25629318
Type 1 diabetes (T1D) is caused by autoimmune disease that leads to the destruction of pancreatic β-cells. Transplantation of cadaveric pancreatic organs or pancreatic islets can restore normal physiology. However,...
7.
Zavazava N
Curr Opin Organ Transplant . 2014 Oct; 19(6):598-602. PMID: 25333832
Purpose Of Review: Embryonic stem cells and induced pluripotent stem cells are pluripotent and therefore capable of differentiating into different cell types and tissues. However, their clinical potential, so far,...
8.
Das S, Jena S, Kim E, Zavazava N, Levasseur D
J Stem Cell Res Ther . 2014 Aug; Suppl 10:009. PMID: 25077040
Introduction: The potential of pluripotent stem cells to be used for cell therapy depends on a comprehensive understanding of the molecular mechanisms underlying their unique ability to specify cells of...
9.
Manzar G, Kim E, Rotti P, Zavazava N
Immunol Res . 2014 May; 59(1-3):279-86. PMID: 24838150
Type I diabetes (T1D) is a chronic autoimmune disease caused by pancreatic β-cell destruction induced by autoantibodies and autoreactive T cells. After significant reduction of the β-cell mass, diabetes sets...
10.
Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N
Immunology . 2014 Feb; 142(3):421-30. PMID: 24527810
Murine embryonic stem (ES) cell-derived haematopoietic progenitor cells (HPCs) engraft and populate lymphoid organs. In vivo, HPCs engraft across MHC barriers protecting donor-type allografts from rejection. However, the underlying phenomenon...