Nicholas Schultheis
Overview
Explore the profile of Nicholas Schultheis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
27
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Altering heparan sulfate suppresses cell abnormalities and neuron loss in model of Alzheimer Disease
Schultheis N, Connell A, Kapral A, Becker R, Mueller R, Shah S, et al.
iScience
. 2024 Aug;
27(7):110256.
PMID: 39109174
We examined the function of heparan-sulfate-modified proteoglycans (HSPGs) in pathways affecting Alzheimer disease (AD)-related cell pathology in human cell lines and mouse astrocytes. Mechanisms of HSPG influences on dependent cell...
2.
Schultheis N, Connell A, Kapral A, Becker R, Mueller R, Shah S, et al.
bioRxiv
. 2024 Feb;
PMID: 38328107
Mutations in are the most common cause of familial, early-onset Alzheimer's disease (AD), typically producing cognitive deficits in the fourth decade. A variant of , was found associated with protection...
3.
Schultheis N, Becker R, Berhanu G, Kapral A, Roseman M, Shah S, et al.
Front Genet
. 2023 Jan;
13:1012706.
PMID: 36699460
Heparan sulfate modified proteins or proteoglycans (HSPGs) are an abundant class of cell surface and extracellular matrix molecules. They serve important co-receptor functions in the regulation of signaling as well...
4.
Tillo M, Lamanna W, Dwyer C, Sandoval D, Pessentheiner A, Al-Azzam N, et al.
J Biol Chem
. 2022 Jun;
298(8):102159.
PMID: 35750212
Lysosomal storage diseases result in various developmental and physiological complications, including cachexia. To study the causes for the negative energy balance associated with cachexia, we assessed the impact of sulfamidase...
5.
Schultheis N, Jiang M, Selleck S
Matrix Biol
. 2021 Feb;
100-101:173-181.
PMID: 33548399
Autophagy is a fundamental cellular process discovered as a response to nutrient deprivation. It provides the cellular and molecular machinery for catabolism of cellular constituents, generating energy and providing building...
6.
Reynolds-Peterson C, Xu J, Zhao N, Cruse C, Yonel B, Trasorras C, et al.
G3 (Bethesda)
. 2019 Nov;
10(1):129-141.
PMID: 31672849
Autophagy is a catabolic process that provides cells with energy and molecular building blocks during nutritional stress. Autophagy also removes misfolded proteins and damaged organelles, a critical mechanism for cellular...