Nicholas Rotile
Overview
Explore the profile of Nicholas Rotile including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
102
Followers
0
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Recent Articles
1.
Esfahani S, Ma H, Krishna S, Shuvaev S, Sabbagh M, Deffler C, et al.
Theranostics
. 2024 Sep;
14(15):5745-5761.
PMID: 39346545
Pancreatic ductal adenocarcinoma (PDAC) is an invasive and rapidly progressive malignancy. A major challenge in patient management is the lack of a reliable imaging tool to monitor tumor response to...
2.
Moon B, Zhou I, Ning Y, Chen Y, Le Fur M, Shuvaev S, et al.
J Am Heart Assoc
. 2024 Jul;
13(14):e034363.
PMID: 38979786
Background: Aging-associated left ventricular dysfunction promotes cardiopulmonary fibrogenic remodeling, Group 2 pulmonary hypertension (PH), and right ventricular failure. At the time of diagnosis, cardiac function has declined, and cardiopulmonary fibrosis...
3.
Le Fur M, Ross A, Pantazopoulos P, Rotile N, Zhou I, Caravan P, et al.
Cancer Nanotechnol
. 2021 Sep;
12(1).
PMID: 34531932
Background: In our earlier work, we identified microRNA-10b (miR10b) as a master regulator of the viability of metastatic tumor cells. This knowledge allowed us to design a miR10b-targeted therapeutic consisting...
4.
Rodriguez-Rodriguez A, Shuvaev S, Rotile N, Jones C, Probst C, Ferreira D, et al.
ACS Sens
. 2019 Aug;
4(9):2412-2419.
PMID: 31397156
An amplifiable magnetic resonance imaging (MRI) probe that combines the stability of the macrocyclic Gd-DOTAGA core with a peroxidase-reactive 5-hydroxytryptamide (5-HT) moiety is reported. The incubation of the complex under...
5.
Desogere P, Tapias L, Rietz T, Rotile N, Blasi F, Day H, et al.
J Nucl Med
. 2017 Jun;
58(12):1991-1996.
PMID: 28611243
There is a large unmet need for a simple, accurate, noninvasive, quantitative, and high-resolution imaging modality to detect lung fibrosis at early stage and to monitor disease progression. Overexpression of...
6.
Zhu B, Wei L, Rotile N, Day H, Rietz T, Farrar C, et al.
Hepatology
. 2017 Jan;
65(3):1015-1025.
PMID: 28039886
Conclusion: Collagen molecular MR imaging is complementary to MR elastography, and combining the two techniques in a single exam leads to increased diagnostic accuracy for all stages of fibrosis. (Hepatology...
7.
Boros E, Holland J, Kenton N, Rotile N, Caravan P
Chempluschem
. 2016 Sep;
81(3):274-281.
PMID: 27630807
Four novel chelators (-) and their zirconium complexes were prepared and compared with the zirconium desferrioxamine B (DFO) complex. The new chelates are based on 1,4,7,10-tetraazacyclododecane (cyclen) and 1,4,8,11-tetraazacyclotetradecane (cyclam)...
8.
Boros E, Rybak-Akimova E, Holland J, Rietz T, Rotile N, Blasi F, et al.
Mol Pharm
. 2013 Dec;
11(2):617-29.
PMID: 24294970
In developing targeted probes for positron emission tomography (PET) based on (64)Cu, stable complexation of the radiometal is key, and a flexible handle for bioconjugation is highly advantageous. Here, we...