Nicholas P Tobin
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Explore the profile of Nicholas P Tobin including associated specialties, affiliations and a list of published articles.
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49
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1053
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Recent Articles
1.
Johansson A, Dar H, Nordenskjold A, Perez-Tenorio G, Tobin N, Yau C, et al.
J Natl Cancer Inst
. 2024 Dec;
PMID: 39656627
Background: Estrogen receptor-positive breast cancer patients have a long-term risk of distant metastatic disease, and premenopausal patients have a higher risk. Randomized studies with long-term follow-up are essential to understand...
2.
Fonseca P, Cui W, Struyf N, Tong L, Chaurasiya A, Casagrande F, et al.
J Exp Clin Cancer Res
. 2024 Apr;
43(1):107.
PMID: 38594748
Background: Tumor cells have the ability to invade and form small clusters that protrude into adjacent tissues, a phenomenon that is frequently observed at the periphery of a tumor as...
3.
Castresana-Aguirre M, Johansson A, Matikas A, Foukakis T, Lindstrom L, Tobin N
Breast Cancer Res
. 2024 Mar;
26(1):38.
PMID: 38454481
Background: The clinical utility of gene signatures in older breast cancer patients remains unclear. We aimed to determine signature prognostic capacity in this patient subgroup. Methods: Research versions of the...
4.
Lundberg A, Yi J, Lindstrom L, Tobin N
NPJ Precis Oncol
. 2022 Aug;
6(1):59.
PMID: 35987928
Genomic alterations resulting in loss of control over the cell cycle is a fundamental hallmark of human malignancies. Whilst pan-cancer studies have broadly assessed tumour genomics and their impact on...
5.
Johansson A, Dar H, J van t Veer L, Tobin N, Perez-Tenorio G, Nordenskjold A, et al.
J Clin Oncol
. 2022 Jul;
40(35):4071-4082.
PMID: 35862873
Purpose: To assess the long-term (20-year) endocrine therapy benefit in premenopausal patients with breast cancer. Methods: Secondary analysis of the Stockholm trial (STO-5, 1990-1997) randomly assigning 924 premenopausal patients to...
6.
Jeuken G, Tobin N, Kall L
PLoS Comput Biol
. 2022 Mar;
18(3):e1010020.
PMID: 35344554
High throughput biology enables the measurements of relative concentrations of thousands of biomolecules from e.g. tissue samples. The process leaves the investigator with the problem of how to best interpret...
7.
Johansson A, Yu N, Iftimi A, Tobin N, van t Veer L, Nordenskjold B, et al.
Int J Cancer
. 2022 Feb;
150(12):2072-2082.
PMID: 35179782
The metastatic potential of estrogen receptor (ER)-positive breast cancers is heterogeneous and distant recurrences occur months to decades after primary diagnosis. We have previously shown that patients with tumors classified...
8.
Ugalde-Morales E, Grassmann F, Humphreys K, Li J, Eriksson M, Tobin N, et al.
Eur J Cancer
. 2022 Jan;
162:194-205.
PMID: 35026490
Background: The aggressive nature of breast cancers detected between planned mammographic screens, so-called interval cancers, remains elusive. Here, we aim to characterise underlying molecular features of interval cancer. Methods: From...
9.
Yang M, Johnsson P, Brautigam L, Yang X, Thrane K, Gao J, et al.
Genet Med
. 2021 Dec;
24(1):157-169.
PMID: 34906508
Purpose: More than half of the familial cutaneous melanomas have unknown genetic predisposition. This study aims at characterizing a novel melanoma susceptibility gene. Methods: We performed exome and targeted sequencing...
10.
Zhang Y, Zhang Y, Kameishi S, Barutello G, Zheng Y, Tobin N, et al.
Cell Rep
. 2021 Aug;
36(8):109616.
PMID: 34433061
Vascular development is a complex multistep process involving the coordination of cellular functions such as migration, proliferation, and differentiation. How mechanical forces generated by cells and transmission of these physical...