Nicholas J Van Zee
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Explore the profile of Nicholas J Van Zee including associated specialties, affiliations and a list of published articles.
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7
Citations
44
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Recent Articles
1.
Van Zee N, Peroutka A, Hillmyer M, Lodge T
Langmuir
. 2023 May;
39(21):7258-7267.
PMID: 37187170
Poloxamers, also known by their trade name, Pluronics, are known to mitigate damage to cellular membranes. However, the mechanism underlying this protection is still unclear. We investigated the effect of...
2.
Hassler J, Van Zee N, Crabtree A, Bates F, Hackel B, Lodge T
ACS Macro Lett
. 2022 May;
11(4):460-467.
PMID: 35575325
Bottlebrush polymers are characterized by an expansive parameter space, including graft length and spacing along the backbone, and these features impact various structural and physical properties such as molecular diffusion...
3.
Van Zee N, Peroutka A, Crabtree A, Hillmyer M, Lodge T
Biomacromolecules
. 2022 Feb;
23(3):1433-1442.
PMID: 35132851
Poloxamers consisting of poly(ethylene oxide) (PEO) and poly(propylene oxide) segments can protect cell membranes against various forms of stress. We investigated the role of the hydrophobic block chemistry on polymer/membrane...
4.
Van Zee N, Hillmyer M, Lodge T
ACS Appl Bio Mater
. 2022 Jan;
3(10):7243-7254.
PMID: 35019383
Amorphous solid dispersions (ASDs) of crystallizable drugs and polymer excipients are attractive for enhancing the solubility and bioavailability of hydrophobic drug molecules. In this study, the solution behavior of poly(-isopropylacrylamide--,-dimethylacrylamide)...
5.
Werber J, Peterson C, Van Zee N, Hillmyer M
Langmuir
. 2020 Dec;
37(1):490-498.
PMID: 33369411
Self-assembled polymer nanoparticles have tremendous potential in biomedical and environmental applications. For all applications, tailored polymer chemistries are critical. In this study, we demonstrate a precursor approach in which an...
6.
Ricarte R, Van Zee N, Li Z, Johnson L, Lodge T, Hillmyer M
Mol Pharm
. 2019 Sep;
16(10):4089-4103.
PMID: 31487183
Many pharmaceutical drugs in the marketplace and discovery pipeline suffer from poor aqueous solubility, thereby limiting their effectiveness for oral delivery. The use of an amorphous solid dispersion (ASD), a...
7.
Li Z, Van Zee N, Bates F, Lodge T
ACS Nano
. 2019 Jan;
13(2):1232-1243.
PMID: 30648859
The effects of cross-link density and composition on the loading and in vitro dissolution of the drug phenytoin as amorphous solid dispersions in emulsion polymerized poly( N-isopropylacrylamide) (PNIPAm) and poly(...