Nicholas De Lay
Overview
Explore the profile of Nicholas De Lay including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
654
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Recent Articles
1.
Parker A, Cureoglu S, De Lay N, Majdalani N, Gottesman S
Mol Microbiol
. 2017 May;
105(2):309-325.
PMID: 28470798
Small regulatory RNAs have major roles in many regulatory circuits in Escherichia coli and other bacteria, including the transition from planktonic to biofilm growth. We tested Hfq-dependent sRNAs in E....
2.
Fan Y, Wu J, Ung M, De Lay N, Cheng C, Ling J
Nucleic Acids Res
. 2015 Jan;
43(3):1740-8.
PMID: 25578967
Accurate flow of genetic information from DNA to protein requires faithful translation. An increased level of translational errors (mistranslation) has therefore been widely considered harmful to cells. Here we demonstrate...
3.
De Lay N, Schu D, Gottesman S
J Biol Chem
. 2013 Jan;
288(12):7996-8003.
PMID: 23362267
A large group of bacterial small regulatory RNAs (sRNAs) use the Hfq chaperone to mediate pairing with and regulation of mRNAs. Recent findings help to clarify how Hfq acts and...
4.
De Lay N, Gottesman S
Mol Cell
. 2012 Oct;
47(6):825-6.
PMID: 23020853
In this issue of Molecular Cell, Bandyra et al. (2012) describe how a bacterial sRNA can lead to degradation of an mRNA by pairing within the coding region of the...
5.
De Lay N, Gottesman S
Mol Microbiol
. 2012 Aug;
86(3):524-38.
PMID: 22925049
Small Hfq-dependent non-coding regulatory RNAs (sRNAs) that alter mRNA stability and expression by pairing with target mRNAs have increasingly been shown to be important in influencing the behaviour of bacteria....
6.
Thomason M, Fontaine F, De Lay N, Storz G
Mol Microbiol
. 2012 Feb;
84(1):17-35.
PMID: 22289118
In bacteria, many small regulatory RNAs (sRNAs) are induced in response to specific environmental signals or stresses and act by base-pairing with mRNA targets to affect protein translation or mRNA...
7.
De Lay N, Gottesman S
RNA
. 2011 Apr;
17(6):1172-89.
PMID: 21527671
In Escherichia coli, many small noncoding regulatory RNAs (sRNAs) post-transcriptionally regulate gene expression by base-pairing to mRNAs in a process that is mediated by the RNA chaperone Hfq. Binding of...
8.
De Lay N, Gottesman S
J Bacteriol
. 2008 Nov;
191(2):461-76.
PMID: 18978044
Small noncoding regulatory RNAs (sRNAs) play a key role in regulating the expression of many genes in Escherichia coli and other bacteria. Many of the sRNAs identified in E. coli...