Nicholas D Bonawitz
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Explore the profile of Nicholas D Bonawitz including associated specialties, affiliations and a list of published articles.
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20
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1860
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Recent Articles
1.
Kim J, Hidalgo-Shrestha C, Bonawitz N, Franke R, Chapple C
J Exp Bot
. 2021 Feb;
72(8):3061-3073.
PMID: 33585900
Cinnamate 4-hydroxylase (C4H) is a cytochrome P450-dependent monooxygenase that catalyzes the second step of the general phenylpropanoid pathway. Arabidopsis reduced epidermal fluorescence 3 (ref3) mutants, which carry hypomorphic mutations in...
2.
Bonawitz N, Ainley W, Itaya A, Chennareddy S, Cicak T, Effinger K, et al.
Plant Biotechnol J
. 2018 Sep;
17(4):750-761.
PMID: 30220095
Emerging genome editing technologies hold great promise for the improvement of agricultural crops. Several related genome editing methods currently in development utilize engineered, sequence-specific endonucleases to generate DNA double strand...
3.
Sullivan M, Bonawitz N
Plant Sci
. 2018 Apr;
269:148-152.
PMID: 29606213
Hydroxycinnamoyl-Coenzyme A (CoA) hydroxycinnamoyl transferases are BAHD family acyltransferases that transfer hydroxycinnamoyl moieties from a CoA-thioester to an acceptor amine or alcohol to form an N-hydroxycinnamoyl amide or O-hydroxycinnamoyl ester,...
4.
Dolan W, Dilkes B, Stout J, Bonawitz N, Chapple C
Plant Cell
. 2017 Dec;
29(12):3269-3285.
PMID: 29203634
The phenylpropanoid pathway is a major global carbon sink and is important for plant fitness and the engineering of bioenergy feedstocks. In , disruption of two subunits of the transcriptional...
5.
Anderson N, Bonawitz N, Nyffeler K, Chapple C
Plant Physiol
. 2015 Jun;
169(3):1557-67.
PMID: 26048881
Phenylpropanoids are phenylalanine-derived specialized metabolites and include important structural components of plant cell walls, such as lignin and hydroxycinnamic acids, as well as ultraviolet and visible light-absorbing pigments, such as...
6.
Bonawitz N, Kim J, Tobimatsu Y, Ciesielski P, Anderson N, Ximenes E, et al.
Nature
. 2014 Mar;
509(7500):376-80.
PMID: 24670657
Lignin is a phenylpropanoid-derived heteropolymer important for the strength and rigidity of the plant secondary cell wall. Genetic disruption of lignin biosynthesis has been proposed as a means to improve...
7.
Bonawitz N, Chapple C
Curr Opin Biotechnol
. 2012 Dec;
24(2):336-43.
PMID: 23228388
The secondary cell wall polymer lignin impedes the extraction of fermentable sugars from biomass, and has been one of the major impediments in the development of cost-effective biofuel technologies. Unfortunately,...
8.
Bonawitz N, Soltau W, Blatchley M, Powers B, Hurlock A, Seals L, et al.
J Biol Chem
. 2011 Dec;
287(8):5434-45.
PMID: 22167189
The plant phenylpropanoid pathway produces an array of metabolites that impact human health and the utility of feed and fiber crops. We previously characterized several Arabidopsis thaliana mutants with dominant...
9.
Banks J, Nishiyama T, Hasebe M, Bowman J, Gribskov M, dePamphilis C, et al.
Science
. 2011 May;
332(6032):960-3.
PMID: 21551031
Vascular plants appeared ~410 million years ago, then diverged into several lineages of which only two survive: the euphyllophytes (ferns and seed plants) and the lycophytes. We report here the...
10.
Bonawitz N, Chapple C
Annu Rev Genet
. 2010 Sep;
44:337-63.
PMID: 20809799
The processes underlying lignification, which for many years have been the near-exclusive purview of chemists and biochemists, have more recently been approached using both classical forward genetic screens and targeted...