Nicholas C Gomez
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Explore the profile of Nicholas C Gomez including associated specialties, affiliations and a list of published articles.
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14
Citations
879
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Recent Articles
1.
Simon J, Gomez N
Methods Mol Biol
. 2020 Dec;
2226:285-302.
PMID: 33326110
Ewing sarcoma is a highly malignant tumor characterized by a chromosomal translocation that modifies the activity of an ETS family transcription factor. The most prevalent translocation product, EWSR1-FLI1, exploits a...
2.
Infarinato N, Stewart K, Yang Y, Gomez N, Pasolli H, Hidalgo L, et al.
Genes Dev
. 2020 Nov;
34(23-24):1713-1734.
PMID: 33184221
Through recurrent bouts synchronous with the hair cycle, quiescent melanocyte stem cells (McSCs) become activated to generate proliferative progeny that differentiate into pigment-producing melanocytes. The signaling factors orchestrating these events...
3.
Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E
Elife
. 2019 Sep;
8.
PMID: 31556874
During mammalian embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis. As effectors of cytoskeletal dynamics, Rho GTPases and their regulators are likely involved, but their daunting complexity has hindered...
4.
Ellis S, Gomez N, Levorse J, Mertz A, Ge Y, Fuchs E
Nature
. 2019 May;
569(7757):497-502.
PMID: 31092920
Cell competition-the sensing and elimination of less fit 'loser' cells by neighbouring 'winner' cells-was first described in Drosophila. Although cell competition has been proposed as a selection mechanism to optimize...
5.
Gallegos Z, Taus P, Gibbs Z, McGlynn K, Gomez N, Davis I, et al.
Mol Cell Biol
. 2019 May;
39(14).
PMID: 31036566
Ewing sarcoma is characterized by a pathognomonic chromosomal translocation that generates the EWSR1-FLI1 chimeric transcription factor. The transcriptional targets of EWSR1-FLI1 that are essential for tumorigenicity are incompletely defined. Here,...
6.
Naik S, Larsen S, Gomez N, Alaverdyan K, Sendoel A, Yuan S, et al.
Nature
. 2018 Jul;
560(7716):E2.
PMID: 29973713
In Fig. 2g of this Article, a panel was inadvertently duplicated. The 'D30 IMQ' image was a duplicate of the 'D6 Ctrl' image. Fig. 2g has been corrected online to...
7.
Naik S, Larsen S, Gomez N, Alaverdyan K, Sendoel A, Yuan S, et al.
Nature
. 2017 Oct;
550(7677):475-480.
PMID: 29045388
The skin barrier is the body's first line of defence against environmental assaults, and is maintained by epithelial stem cells (EpSCs). Despite the vulnerability of EpSCs to inflammatory pressures, neither...
8.
Ge Y, Gomez N, Adam R, Nikolova M, Yang H, Verma A, et al.
Cell
. 2017 Apr;
169(4):636-650.e14.
PMID: 28434617
Tissue stem cells contribute to tissue regeneration and wound repair through cellular programs that can be hijacked by cancer cells. Here, we investigate such a phenomenon in skin, where during...
9.
Sendoel A, Dunn J, Rodriguez E, Naik S, Gomez N, Hurwitz B, et al.
Nature
. 2017 Jan;
541(7638):494-499.
PMID: 28077873
We are just beginning to understand how translational control affects tumour initiation and malignancy. Here we use an epidermis-specific, in vivo ribosome profiling strategy to investigate the translational landscape during...
10.
Gomez N, Hepperla A, Dumitru R, Simon J, Fang F, Davis I
Cell Rep
. 2016 Nov;
17(6):1607-1620.
PMID: 27806299
Chromatin regulation is critical for differentiation and disease. However, features linking the chromatin environment of stem cells with disease remain largely unknown. We explored chromatin accessibility in embryonic and multipotent...