Nibaldo C Inestrosa
Overview
Explore the profile of Nibaldo C Inestrosa including associated specialties, affiliations and a list of published articles.
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259
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7687
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Recent Articles
1.
Jara C, Torres A, Park-Kang H, Sandoval L, Retamal C, Gonzalez A, et al.
Neurotox Res
. 2025 Jan;
43(1):3.
PMID: 39775210
Mitochondria produces energy through oxidative phosphorylation (OXPHOS), maintaining calcium homeostasis, survival/death cell signaling mechanisms, and redox balance. These mitochondrial functions are especially critical for neurons. The hippocampus is crucial for...
2.
Parodi J, Mira R, Fuenzalida M, Cerpa W, Serrano F, Tapia-Rojas C, et al.
Cell Mol Neurobiol
. 2024 Nov;
44(1):76.
PMID: 39535658
Wnt signaling plays a role in synaptic plasticity, but the specific cellular events and molecular components involved in Wnt signaling-mediated synaptic plasticity are not well defined. Here, we report a...
3.
Parodi J, Mira R, Martinez-Torres A, Inestrosa N
Biochem Biophys Res Commun
. 2024 Aug;
738:150507.
PMID: 39154550
Wnt signaling plays an essential role in cellular processes like development, maturation, and function maintenance. Xenopus laevis oocytes are a suitable model to study not only the development but also...
4.
Rios J, Borquez J, Godoy J, Zolezzi J, Furrianca M, Inestrosa N
Ageing Res Rev
. 2024 Jul;
100:102439.
PMID: 39074563
Alzheimer's disease (AD) constitutes a major public-health issue of our time. Regrettably, despite our considerable understanding of the pathophysiological aspects of this disease, current interventions lead to poor outcomes. Furthermore,...
5.
Godoy J, Mira R, Inestrosa N
Ageing Res Rev
. 2024 Jun;
99:102396.
PMID: 38942199
Lithium therapy received approval during the 1970s, and it has been used for its antidepressant, antimanic, and anti-suicidal effects for acute and long-term prophylaxis and treatment of bipolar disorder (BPD)....
6.
Torres A, Fleischhart V, Inestrosa N
Front Cell Dev Biol
. 2024 Jun;
12:1405393.
PMID: 38882057
Mitochondria are key organelles for the optimal function of the cell. Among their many functions, they maintain protein homeostasis through their own proteostatic machinery, which involves proteases and chaperones that...
7.
Schwarz K, Vicencio S, Inestrosa N, Villaseca P, Del Rio R
J Physiol
. 2023 Dec;
602(2):263-280.
PMID: 38064358
Cardiovascular diseases (CVD) and neurodegenerative disorders, such as Alzheimer's disease (AD), are highly prevalent conditions in middle-aged women that severely impair quality of life. Recent evidence suggests the existence of...
8.
Martinez A, Lamaizon C, Valls C, Llambi F, Leal N, Fitzgerald P, et al.
Antioxidants (Basel)
. 2023 Nov;
12(11).
PMID: 38001860
The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however,...
9.
Oliva C, Lira M, Jara C, Catenaccio A, Mariqueo T, Lindsay C, et al.
Front Aging Neurosci
. 2023 Oct;
15:1250342.
PMID: 37810621
Social interactions have a significant impact on health in humans and animal models. Social isolation initiates a cascade of stress-related physiological disorders and stands as a significant risk factor for...
10.
Cisternas P, Gherardelli C, Gutierrez J, Salazar P, Mendez-Orellana C, Wong G, et al.
Front Endocrinol (Lausanne)
. 2023 Sep;
14:1237796.
PMID: 37732123
Metabolic syndrome (MetS), a cluster of metabolic conditions that include obesity, hyperlipidemia, and insulin resistance, increases the risk of several aging-related brain diseases, including Alzheimer's disease (AD). However, the underlying...