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Neville Anthony

Explore the profile of Neville Anthony including associated specialties, affiliations and a list of published articles. Areas
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Citations 18
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Recent Articles
1.
Vaswani R, Huang D, Anthony N, Xu L, Centore R, Schiller S, et al.
J Med Chem . 2025 Jan; 68(2):1772-1792. PMID: 39801091
BRM (SMARCA2) and BRG1 (SMARCA4) are mutually exclusive ATPase subunits of the mSWI/SNF (BAF) chromatin remodeling complex. BAF is an attractive therapeutic target because of its role in transcription, and...
2.
Zhang H, Lapointe B, Anthony N, Azevedo R, Cals J, Correll C, et al.
ACS Med Chem Lett . 2020 Feb; 11(2):114-119. PMID: 32071676
The clinical success of anti-IL-17 monoclonal antibodies (i.e., Cosentyx and Taltz) has validated Th17 pathway modulation for the treatment of autoimmune diseases. The nuclear hormone receptor RORγt is a master...
3.
Gomez R, Jolly S, Williams T, Tucker T, Tynebor R, Vacca J, et al.
Bioorg Med Chem Lett . 2011 Nov; 21(24):7344-50. PMID: 22071300
Next generation NNRTIs are sought which possess both broad spectrum antiviral activity against key mutant strains and a high genetic barrier to the selection of new mutant viral strains. Pyridones...
4.
Gomez R, Jolly S, Williams T, Vacca J, Torrent M, McGaughey G, et al.
J Med Chem . 2011 Oct; 54(22):7920-33. PMID: 21985673
Highly active antiretroviral therapy (HAART) significantly reduces human immunodeficiency virus (HIV) viral load and has led to a dramatic decrease in acquired immunodeficiency syndrome (AIDS) related mortality. Despite this success,...