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Netty G Santoso

Explore the profile of Netty G Santoso including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 191
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Recent Articles
1.
Li T, Park Y, Watters E, Wang X, Zhou D, Fiches G, et al.
Antiviral Res . 2024 Jun; 228:105947. PMID: 38925368
Combinational antiretroviral therapy (cART) suppresses human immunodeficiency virus type 1 (HIV-1) viral replication and pathogenesis in acquired immunodeficiency syndrome (AIDS) patients. However, HIV-1 remains in the latent stage of infection...
2.
Zhou D, Wu Z, Park J, Fiches G, Li T, Ma Q, et al.
Nucleic Acids Res . 2022 Jul; 50(15):8700-8718. PMID: 35904816
FACT (FAcilitates Chromatin Transcription) is a heterodimeric protein complex composed of SUPT16H and SSRP1, and a histone chaperone participating in chromatin remodeling during gene transcription. FACT complex is profoundly regulated,...
3.
Fiches G, Wu Z, Zhou D, Biswas A, Li T, Kong W, et al.
PLoS Pathog . 2022 Apr; 18(4):e1010503. PMID: 35486659
Polyamines are critical metabolites involved in various cellular processes and often dysregulated in cancers. Kaposi's sarcoma-associated Herpesvirus (KSHV), a defined human oncogenic virus, leads to profound alterations of host metabolic...
4.
Biswas A, Zhou D, Fiches G, Wu Z, Liu X, Ma Q, et al.
PLoS Pathog . 2021 Jul; 17(7):e1009764. PMID: 34297745
Both Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) establish the persistent, life-long infection primarily at the latent status, and associate with certain types of tumors, such as B cell...
5.
Jean M, Zhou D, Fiches G, Kong W, Huang H, Purmal A, et al.
J Med Virol . 2019 Apr; 91(8):1571-1576. PMID: 30989696
A cure for human immunodeficiency virus type-1 (HIV-1) has been hampered by the limitation of current combination antiretroviral therapy (cART) to address the latent reservoirs in HIV-1 patients. One strategy...
6.
Simpson S, Fiches G, Jean M, Dieringer M, McGuinness J, John S, et al.
Front Microbiol . 2018 May; 9:788. PMID: 29740418
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus responsible for the development of Kaposi's sarcoma, primary effusion lymphoma (PEL), and Multicentric Castleman's disease in immunocompromised individuals. Despite the burden of...
7.
Jean M, Hayashi T, Huang H, Brennan J, Simpson S, Purmal A, et al.
Front Microbiol . 2017 Nov; 8:2007. PMID: 29089933
Despite combination antiretroviral therapy (cART), acquired immunodeficiency syndrome (AIDS), predominantly caused by the human immunodeficiency virus type 1 (HIV-1), remains incurable. The barrier to a cure lies in the virus'...
8.
Hayashi T, Jean M, Huang H, Simpson S, Santoso N, Zhu J
Antiviral Res . 2017 Aug; 146:76-85. PMID: 28842263
Combination antiretroviral therapy (cART) has been proven to efficiently inhibit ongoing replication of human immunodeficiency virus type 1 (HIV-1), and significantly improve the health outcome in patients of acquired immune...
9.
Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, et al.
Front Microbiol . 2017 Jun; 8:1035. PMID: 28638377
While combinatory antiretroviral therapy (cART) can effectively reduce HIV-1 viremia, it cannot eliminate HIV-1 infection. In the presence of cART, viral reservoirs remain latent, impeding the cure of HIV-1/AIDS. Recently,...
10.
Santoso N, Cebotaru L, Guggino W
Cell Physiol Biochem . 2011 Jun; 27(6):715-26. PMID: 21691089
Dysregulation of Ca(2+) signaling and homeostasis has been linked to the development of ADPKD through aberrant functioning of the polycystins. In this study, we investigated the role of the polycystins...