Guillaume N Fiches
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Explore the profile of Guillaume N Fiches including associated specialties, affiliations and a list of published articles.
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11
Citations
156
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Recent Articles
1.
Li T, Park Y, Watters E, Wang X, Zhou D, Fiches G, et al.
Antiviral Res
. 2024 Jun;
228:105947.
PMID: 38925368
Combinational antiretroviral therapy (cART) suppresses human immunodeficiency virus type 1 (HIV-1) viral replication and pathogenesis in acquired immunodeficiency syndrome (AIDS) patients. However, HIV-1 remains in the latent stage of infection...
2.
Li T, Kenney A, Park J, Fiches G, Liu H, Zhou D, et al.
Front Immunol
. 2022 Sep;
13:1007089.
PMID: 36177032
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results...
3.
Zhou D, Wu Z, Park J, Fiches G, Li T, Ma Q, et al.
Nucleic Acids Res
. 2022 Jul;
50(15):8700-8718.
PMID: 35904816
FACT (FAcilitates Chromatin Transcription) is a heterodimeric protein complex composed of SUPT16H and SSRP1, and a histone chaperone participating in chromatin remodeling during gene transcription. FACT complex is profoundly regulated,...
4.
Fiches G, Wu Z, Zhou D, Biswas A, Li T, Kong W, et al.
PLoS Pathog
. 2022 Apr;
18(4):e1010503.
PMID: 35486659
Polyamines are critical metabolites involved in various cellular processes and often dysregulated in cancers. Kaposi's sarcoma-associated Herpesvirus (KSHV), a defined human oncogenic virus, leads to profound alterations of host metabolic...
5.
Biswas A, Zhou D, Fiches G, Wu Z, Liu X, Ma Q, et al.
PLoS Pathog
. 2021 Jul;
17(7):e1009764.
PMID: 34297745
Both Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) establish the persistent, life-long infection primarily at the latent status, and associate with certain types of tumors, such as B cell...
6.
Li T, Kenney A, Liu H, Fiches G, Zhou D, Biswas A, et al.
bioRxiv
. 2021 Jun;
PMID: 34075374
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results...
7.
Zhou D, Park J, Wu Z, Huang H, Fiches G, Biswas A, et al.
bioRxiv
. 2021 Apr;
PMID: 33907746
FACT ( FA cilitates C hromatin T ranscription) is a heterodimeric protein complex composed of SUPT16H and SSRP1, and a histone chaperone participating in chromatin remodeling during gene transcription. FACT...
8.
Fiches G, Zhou D, Kong W, Biswas A, Ahmed E, Baiocchi R, et al.
PLoS Pathog
. 2020 Aug;
16(8):e1008778.
PMID: 32841292
EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation. In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the...
9.
Fiches G, Eyre N, Aloia A, van der Hoek K, Betz-Stablein B, Luciani F, et al.
Virology
. 2016 Mar;
493:60-74.
PMID: 26999027
The spatiotemporal dynamics of Hepatitis C Virus (HCV) RNA localisation are poorly understood. To address this we engineered HCV genomes harbouring MS2 bacteriophage RNA stem-loops within the 3'-untranslated region to...
10.
Eyre N, Fiches G, Aloia A, Helbig K, McCartney E, McErlean C, et al.
J Virol
. 2014 Jan;
88(7):3636-52.
PMID: 24429364
Unlabelled: Hepatitis C virus (HCV) NS5A is essential for viral genome replication within cytoplasmic replication complexes and virus assembly at the lipid droplet (LD) surface, although its definitive functions are...