Nerymar Ortiz-Otero
Overview
Explore the profile of Nerymar Ortiz-Otero including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
164
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Recent Articles
1.
Ortiz-Otero N, Marshall J, Lash B, King M
Nanoscale Adv
. 2022 Sep;
2(9):3942-3953.
PMID: 36132797
Several studies have demonstrated the role of platelets in promoting cancer metastasis. Platelets bind to and protect circulating tumor cells (CTCs) from hemodynamic forces and immune cells, and also promote...
2.
Ortiz-Otero N, Marshall J, Glenn A, Matloubieh J, Joseph J, Sahasrabudhe D, et al.
BMC Cancer
. 2021 Aug;
21(1):898.
PMID: 34362331
Background: Radical surgery is the first line treatment for localized prostate cancer (PC), however, several studies have demonstrated that surgical procedures induce tumor cell mobilization from the primary tumor into...
3.
Greenlee J, Lopez-Cavestany M, Ortiz-Otero N, Liu K, Subramanian T, Cagir B, et al.
Elife
. 2021 Aug;
10.
PMID: 34342264
Colorectal cancer (CRC) remains a leading cause of cancer death, and its mortality is associated with metastasis and chemoresistance. We demonstrate that oxaliplatin-resistant CRC cells are sensitized to TRAIL-mediated apoptosis....
4.
Hapach L, Carey S, Schwager S, Taufalele P, Wang W, Mosier J, et al.
Cancer Res
. 2021 May;
81(13):3649-3663.
PMID: 33975882
Although intratumoral genomic heterogeneity can impede cancer research and treatment, less is known about the effects of phenotypic heterogeneities. To investigate the role of cell migration heterogeneities in metastasis, we...
5.
Grayson K, Jyotsana N, Ortiz-Otero N, King M
PLoS One
. 2021 Mar;
16(3):e0246733.
PMID: 33661931
Three-dimensional spheroid cultures have been shown to better physiologically mimic the cell-cell and cell-matrix interactions that occur in solid tumors more than traditional 2D cell cultures. One challenge in spheroid...
6.
Ortiz-Otero N, Marshall J, Lash B, King M
BMC Cancer
. 2020 Sep;
20(1):873.
PMID: 32917154
Background: Recent studies have shown that chemotherapy destabilizes the blood vasculature and increases circulating tumor cell (CTC) influx into the circulation of metastatic cancer patients (Met-pa). CTCs are a precursor...
7.
Ortiz-Otero N, Clinch A, Hope J, Wang W, Reinhart-King C, King M
Oncotarget
. 2020 Apr;
11(12):1037-1050.
PMID: 32256977
Previous studies have demonstrated that CTCs do not travel in the bloodstream alone, but rather are accompanied by clusters of stromal cells such as cancer associated fibroblasts (CAFs). Our laboratory...
8.
Ortiz-Otero N, Mohamed Z, King M
Adv Exp Med Biol
. 2018 Oct;
1092:235-251.
PMID: 30368756
Platelets can be considered as the "guardian of hemostasis" where their main function is to maintain vascular integrity. In pathological conditions, the hemostatic role of platelets may be hijacked to...