Nelson Leung Sang Tang
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Explore the profile of Nelson Leung Sang Tang including associated specialties, affiliations and a list of published articles.
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27
Citations
346
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Recent Articles
1.
Huang B, Huang J, Chiang N, Chen Z, Lui G, Ling L, et al.
Front Immunol
. 2024 Jan;
14:1315602.
PMID: 38268924
Introduction: There is insufficient understanding on systemic interferon (IFN) responses during COVID-19 infection. Early reports indicated that interferon responses were suppressed by the coronavirus (SARS-CoV-2) and clinical trials of administration...
2.
Yeung S, Ma S, Wang X, Chen Y, Tsui S, Tang N, et al.
Gerontology
. 2023 Oct;
69(12):1414-1423.
PMID: 37857262
Introduction: Telomere length (TL) is generally regarded as a biomarker of aging. TL, which is influenced by sociodemographic factors, has been shown to be inversely associated with morbidity. However, most...
3.
Ma S, Tang N, Wat K, Tang J, Lau K, Law C, et al.
Am J Alzheimers Dis Other Demen
. 2019 May;
34(5):302-307.
PMID: 31064198
Alzheimer's disease (AD) is the most prevalent form of dementia, and age is strongly associated with the incidence of AD. This study aimed to investigate the association between the genotypes...
4.
Liao J, Ng S, Luk A, Suen H, Qian Y, Lee A, et al.
Development
. 2019 Mar;
146(6).
PMID: 30824552
Neonatal germ cell development provides the foundation of spermatogenesis. However, a systematic understanding of this process is still limited. To resolve cellular and molecular heterogeneity in this process, we profiled...
5.
Qian Y, Liao J, Suen A, Lee A, Chung H, Tang N, et al.
Int J Biochem Cell Biol
. 2018 Dec;
107:1-5.
PMID: 30529019
Single-cell parallel sequencing allows us to explore how genetic and epigenetic variations correlate of gene expression in the same cell. Beads-based approach and non-beads-based approach are the two present methods...
6.
Ma S, Tang N, Lam L
J Psychiatr Res
. 2016 Mar;
76:143-7.
PMID: 26943237
DNA methylation is an important epigenetic mechanism for gene regulation and it is well established there is association between aging and DNA methylation. Alzheimer's disease (AD) is the most common...
7.
Qian Y, Tu J, Tang N, Kong G, Chung J, Chan W, et al.
Int J Biochem Cell Biol
. 2015 May;
67:121-7.
PMID: 25982203
Aging is a complex time-dependent biological process that takes place in every cell and organ, eventually leading to degenerative changes that affect normal biological functions. In the past decades, the...
8.
Tu J, Liao J, Luk A, Tang N, Chan W, Lee T
Int J Biochem Cell Biol
. 2015 May;
67:115-20.
PMID: 25979370
For decades, DNA methylation at the 5 position of cytosine (5mC) catalyzed by DNA methyltransferases (DNMTs) is a well-known epigenetic modification in mammalian genome, where it modulates chromatin remodeling and...
9.
Ma R, Lee H, Lim Lam V, Tam C, Ho J, Zhao H, et al.
PLoS One
. 2014 Jan;
9(1):e84770.
PMID: 24465431
In Asia, young-onset type 2 diabetes (YOD) is characterized by obesity and increased risk for cardiovascular disease (CVD). In a genome-wide association study (GWAS) of 99 Chinese obese subjects with...
10.
Lim Lam V, Ma R, Lee H, Hu C, Park K, Furuta H, et al.
PLoS One
. 2013 Jun;
8(6):e62378.
PMID: 23776430
Type 2 diabetes (T2D) is a complex disease characterized by beta cell dysfunctions. Islet amyloid polypeptide (IAPP) is highly conserved and co-secreted with insulin with over 40% of autopsy cases...