Jiajie Tu
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Explore the profile of Jiajie Tu including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
912
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Recent Articles
1.
Han D, Sun H, Zhang R, Ge H, Guo P, Chu R, et al.
Int J Biol Sci
. 2025 Feb;
21(4):1513-1529.
PMID: 39990667
PDE4D has been reported to exhibit significantly elevated levels in the synovium of RA patients compared with OA, yet its role in RA remains underexplored. This study aimed to elucidate...
2.
Chen Y, Xin Q, Zhu M, Qiu J, Luo Y, Li R, et al.
J Adv Res
. 2025 Jan;
PMID: 39756574
Background: After significant advancements in tumor treatment, personalized cell therapy based on chimeric antigen receptors (CAR) holds promise for transforming the management of various diseases. CAR-T therapy, the first approved...
3.
Chen Y, Xin Q, Zhu M, Qiu J, Qiu J, Li R, et al.
Cell Commun Signal
. 2024 Oct;
22(1):521.
PMID: 39468646
Immune cell therapy based on chimeric antigen receptor (CAR) technology platform has been greatly developed. The types of CAR immune cell therapy have expanded from T cells to innate immune...
4.
Tu J, Chen W, Huang W, Wang X, Fang Y, Wu X, et al.
Ann Rheum Dis
. 2024 Aug;
83(12):1707-1721.
PMID: 39164066
Objectives: T helper 9 (Th9) cells are recognised for their characteristic expression of the transcription factor PU.1 and production of interleukin-9 (IL-9), which has been implicated in various autoimmune diseases....
5.
Tu J, Yan J, Ji X, Liu Q, Qing X
Sensors (Basel)
. 2024 May;
24(9).
PMID: 38733057
Multi-layer complex structures are widely used in large-scale engineering structures because of their diverse combinations of properties and excellent overall performance. However, multi-layer complex structures are prone to interlaminar debonding...
6.
Chen Y, Liu C, Fang Y, Chen W, Qiu J, Zhu M, et al.
Biochem Pharmacol
. 2024 Feb;
222:116066.
PMID: 38373592
Chimeric antigen receptor (CAR)-immune cell therapy has revolutionized the anti-tumor field, achieving efficient and precise tumor clearance by directly guiding immune cell activity to target tumors. In addition, the use...
7.
Fang Y, Huang W, Zhu X, Wang X, Wu X, Wang H, et al.
Arthritis Rheumatol
. 2024 Jan;
76(6):845-856.
PMID: 38221658
Objective: The specific role of fibroblast-like synoviocytes (FLSs) in the pathogenesis of rheumatoid arthritis (RA) is still not fully elucidated. This study aimed to explore the molecular mechanisms of epigenetic...
8.
Chen Y, Zhu X, Liu H, Wang C, Chen Y, Wang H, et al.
J Transl Med
. 2023 Sep;
21(1):654.
PMID: 37740183
Background: The chimeric antigen receptor (CAR)-T therapy has a limited therapeutic effect on solid tumors owing to the limited CAR-T cell infiltration into solid tumors and the inactivation of CAR-T...
9.
Zhang J, Zhang X, Lu M, Chang Y, Wang Q, Tu J, et al.
Pharmaceuticals (Basel)
. 2023 May;
16(5).
PMID: 37242446
G protein-coupled receptor kinase 2 (GRK2) is one of the cytosolic enzymes, and GRK2 translocation induces prostaglandin E2 receptor 4 (EP4) over-desensitization and reduces the level of cyclic adenosine monophosphate...
10.
Zhu X, Fang Y, Chen Y, Chen Y, Hong W, Wei W, et al.
Life Sci
. 2023 Mar;
320:121558.
PMID: 36889666
Glioma is the most common tumor of the primary central nervous system, and its malignant phenotype has been shown to be closely related to glioma stem cells (GSCs). Although temozolomide...