Nazmus Salehin
Overview
Explore the profile of Nazmus Salehin including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
30
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0
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Recent Articles
1.
Proks M, Salehin N, Brickman J
Nat Methods
. 2024 Nov;
22(1):207-216.
PMID: 39543284
The rapid growth of single-cell transcriptomic technology has produced an increasing number of datasets for both embryonic development and in vitro pluripotent stem cell-derived models. This avalanche of data surrounding...
2.
Redo-Riveiro A, Al-Mousawi J, Linneberg-Agerholm M, Proks M, Perera M, Salehin N, et al.
Stem Cell Reports
. 2024 Jan;
19(2):174-186.
PMID: 38215757
In early mammalian development, cleavage stage blastomeres and inner cell mass (ICM) cells co-express embryonic and extra-embryonic transcriptional determinants. Using a protein-based double reporter we identify an embryonic stem cell...
3.
Salehin N, Knowles H, Masamsetti V, Tam P
Biochem Soc Trans
. 2022 Nov;
50(6):1619-1631.
PMID: 36398790
The interplay of signalling input and downstream transcriptional activity is the key molecular attribute driving the differentiation of germ layer tissue and the specification of cell lineages within each germ...
4.
Salehin N, Santucci N, Osteil P, Tam P
Methods Mol Biol
. 2022 Apr;
2490:93-100.
PMID: 35486242
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is used to identify open chromatin regions in cells. This can be used to identify putative regulatory regions, determine dynamics and mechanisms...
5.
Knowles H, Santucci N, Studdert J, Goh H, Kaufman-Francis K, Salehin N, et al.
Genesis
. 2022 Feb;
60(1-2):e23466.
PMID: 35104045
Allocation of cells to an endodermal fate in the gastrulating embryo is driven by Nodal signaling and consequent activation of TGFβ pathway. In vitro methodologies striving to recapitulate the process...
6.
Salehin N, Tam P, Osteil P
J Bioinform Comput Biol
. 2020 Apr;
18(1):2040003.
PMID: 32336246
Assays for transposase-accessible chromatin sequencing (ATAC-seq) provides an innovative approach to study chromatin status in multiple cell types. Moreover, it is also possible to efficiently extract differentially accessible chromatin (DACs)...
7.
McMahon R, Sibbritt T, Salehin N, Osteil P, Tam P
Dev Growth Differ
. 2019 May;
61(5):327-336.
PMID: 31111476
Development of an embryo is driven by a series of molecular instructions that control the differentiation of tissue precursor cells and shape the tissues into major body parts. LIM homeobox...
8.
Osteil P, Studdert J, Goh H, Wilkie E, Fan X, Khoo P, et al.
Development
. 2019 Mar;
146(7).
PMID: 30890572
During embryogenesis, the stringent regulation of Wnt activity is crucial for the morphogenesis of the head and brain. The loss of function of the Wnt inhibitor Dkk1 results in elevated...
9.
Sibbritt T, Osteil P, Fan X, Sun J, Salehin N, Knowles H, et al.
Methods Mol Biol
. 2019 Feb;
1940:77-95.
PMID: 30788819
Efficient and reliable methods for gene editing are critical for the generation of loss-of-gene function stem cells and genetically modified mice. Here, we outline the application of CRISPR-Cas9 technology for...