Naveen Babbar
Overview
Explore the profile of Naveen Babbar including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
893
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0
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Recent Articles
11.
Babbar N, Casero Jr R
Cancer Res
. 2006 Dec;
66(23):11125-30.
PMID: 17145855
Inflammation has been implicated in the development of many human epithelial cancers, including those of the stomach, lung, colon, and prostate. Tumor necrosis factor-alpha (TNF-alpha) is a potent pleiotropic, proinflammatory...
12.
Babbar N, Hacker A, Huang Y, Casero Jr R
J Biol Chem
. 2006 Jun;
281(34):24182-92.
PMID: 16757480
Tumor necrosis factor alpha (TNFalpha) is a potent pleiotropic cytokine produced by many cells in response to inflammatory stress. The molecular mechanisms responsible for the multiple biological activities of TNFalpha...
13.
Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells
Babbar N, Gerner E, Casero Jr R
Biochem J
. 2005 Nov;
394(Pt 1):317-24.
PMID: 16262603
Epidemiological, experimental and clinical results suggest that aspirin and other NSAIDs (non-steroidal anti-inflammatory drugs) inhibit the development of colon cancer. It has been shown that the NSAID sulindac induces apoptosis...
14.
Ignatenko N, Babbar N, Mehta D, Casero Jr R, Gerner E
Mol Carcinog
. 2004 Jan;
39(2):91-102.
PMID: 14750214
An activated Ki-ras was expressed in the human colon adenocarcinoma cell line Caco-2 to study the effects of Ki-ras oncogene on polyamine metabolism during gastrointestinal tumorigenesis. Multiple clones selected for...
15.
Babbar N, Ignatenko N, Casero Jr R, Gerner E
J Biol Chem
. 2003 Sep;
278(48):47762-75.
PMID: 14506281
Sulindac, a non-steroidal anti-inflammatory prodrug, is metabolized into pharmacologically active sulfide and sulfone derivatives. Sulindac sulfide, but not sulindac sulfone, inhibits cyclooxygenase (COX) enzyme activities, yet both derivatives have growth...
16.
Martinez M, OBrien T, Fultz K, Babbar N, Yerushalmi H, Qu N, et al.
Proc Natl Acad Sci U S A
. 2003 Jun;
100(13):7859-64.
PMID: 12810952
Most sporadic colon adenomas acquire mutations in the adenomatous polyposis coli gene (APC) and show defects in APC-dependent signaling. APC influences the expression of several genes, including the c-myc oncogene...