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Nathaniel E Wright

Explore the profile of Nathaniel E Wright including associated specialties, affiliations and a list of published articles. Areas
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Citations 19
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Recent Articles
1.
Wright N, Kennedy D, Ai J, Veselits M, Attaway M, Yoon Y, et al.
bioRxiv . 2024 May; PMID: 38712068
Germinal center (GC) B cells segregate into three subsets that compartmentalize the antagonistic molecular programs of selection, proliferation, and somatic hypermutation. In bone marrow, the epigenetic reader BRWD1 orchestrates and...
2.
Mandal M, Maienschein-Cline M, Hu Y, Mohsin A, Veselits M, Wright N, et al.
Nat Immunol . 2023 Nov; 25(1):129-141. PMID: 37985858
Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination. Transitions between each state require large, coordinated changes in epigenetic landscapes and...
3.
Wright N, Mandal M, Clark M
Trends Immunol . 2023 Aug; 44(9):668-677. PMID: 37573227
In mammals, B cells strictly segregate proliferation from somatic mutation as they develop within the bone marrow and then mature through germinal centers (GCs) in the periphery. Failure to do...
4.
Fike A, Chodisetti S, Wright N, Bricker K, Domeier P, Maienschein-Cline M, et al.
Cell Rep . 2023 May; 42(5):112512. PMID: 37200190
Germinal centers (GCs), sites of antibody affinity maturation, are organized into dark (DZ) and light (LZ) zones. Here, we show a B cell-intrinsic role for signal transducer and activator of...
5.
Press D, Pierce B, Lauderdale D, Aschebrook-Kilfoy B, Gomez S, Hedeker D, et al.
Prev Med Rep . 2020 Oct; 20:101174. PMID: 33088675
African American (AA) men experience more than twice the prostate cancer mortality as White men yet are under-represented in academic research involving prostate-specific antigen (PSA), a biomarker of prostate cancer...
6.
Patamawenu A, Wright N, Shofner T, Evans S, Manion M, Doria-Rose N, et al.
PLoS One . 2019 Dec; 14(12):e0225806. PMID: 31830058
Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus, type I (HIV-1) pathogenesis. PDCs produce IFN-α and other...