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Nathan Hatcher

Explore the profile of Nathan Hatcher including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 103
Followers 0
Related Specialties
Neurology
Biochemistry
Science
Top 10 Co-Authors
Jonathan V Sweedler
Elena V Romanova
Rhanor Gillette
Kurt Potgieter
Elizabeth C Cropper
Lihang Yao
Henry Shion
Jurgen Rybak
David McLaren
David Price
Published In
ACS Chem Neurosci
J Biol Chem
J Neurosci
Sci Rep
Rapid Commun Mass Spectrom
Affiliations
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Recent Articles
1.
Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis
Pastore R, Yao L, Hatcher N, Helley M, Brownlees J, Desai R
Sci Rep . 2025 Jan; 15(1):325. PMID: 39747180
Dysfunction of the endo-lysosomal intracellular Cholesterol transporter 2 protein (NPC2) leads to the onset of Niemann-Pick Disease Type C (NPC), a lysosomal storage disorder. Metabolic and homeostatic mechanisms are disrupted...
2.
cAMP, Ca, pH, and NO Regulate H-like Cation Channels That Underlie Feeding and Locomotion in the Predatory Sea Slug Pleurobranchaea californica
Green D, Huang R, Sudlow L, Hatcher N, Potgieter K, McCrohan C, et al.
ACS Chem Neurosci . 2018 Aug; 9(8):1986-1993. PMID: 30067017
A systems approach to regulation of neuronal excitation in the mollusc Pleurobranchaea has described novel interactions of cyclic AMP-gated cation current (I), Ca, pH, and NO. I appears in many...
3.
Functional Peptidomics: Stimulus- and Time-of-Day-Specific Peptide Release in the Mammalian Circadian Clock
Atkins Jr N, Ren S, Hatcher N, Burgoon P, Mitchell J, Sweedler J, et al.
ACS Chem Neurosci . 2018 Jun; 9(8):2001-2008. PMID: 29901982
Daily oscillations of brain and body states are under complex temporal modulation by environmental light and the hypothalamic suprachiasmatic nucleus (SCN), the master circadian clock. To better understand mediators of...
4.
In vivo isotopically labeled atherosclerotic aorta plaques in ApoE KO mice and molecular profiling by matrix-assisted laser desorption/ionization mass spectrometric imaging
Castro-Perez J, Hatcher N, Kofi Karikari N, Wang S, Mendoza V, Shion H, et al.
Rapid Commun Mass Spectrom . 2014 Oct; 28(22):2471-9. PMID: 25303476
Rationale: The ability to quantify rates of formation, regression and/or remodeling of atherosclerotic plaque should facilitate a better understanding of the pathogenesis and management of cardiovascular disease. In the current...
5.
Distinct mechanisms produce functionally complementary actions of neuropeptides that are structurally related but derived from different precursors
Vilim F, Sasaki K, Rybak J, Alexeeva V, Cropper E, Jing J, et al.
J Neurosci . 2010 Jan; 30(1):131-47. PMID: 20053896
Many bioactive neuropeptides containing RFamide at their C terminus have been described in both invertebrates and vertebrates. To obtain insight into the functional logic of RFamide signaling, we investigate it...
6.
Interfering with nitric oxide measurements. 4,5-diaminofluorescein reacts with dehydroascorbic acid and ascorbic acid
Zhang X, Kim W, Hatcher N, Potgieter K, Moroz L, Gillette R, et al.
J Biol Chem . 2002 Oct; 277(50):48472-8. PMID: 12370177
4,5-Diaminofluorescein (DAF-2) is widely used for detection and imaging of NO based on its sensitivity, noncytotoxicity, and specificity. In the presence of oxygen, NO and NO-related reactive nitrogen species nitrosate...