Natascha Hermann-Kleiter
Overview
Explore the profile of Natascha Hermann-Kleiter including associated specialties, affiliations and a list of published articles.
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45
Citations
1009
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Recent Articles
1.
Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6
Woelk J, Hornsteiner F, Aschauer-Wallner S, Stoitzner P, Baier G, Hermann-Kleiter N
Cell Death Dis
. 2025 Feb;
16(1):77.
PMID: 39920136
Natural killer (NK) cell development and functionality rely on precise regulation by specific transcription factors (TFs). Our study demonstrates that the nuclear orphan receptor NR2F6 represses the expression of the...
2.
Woelk J, Narasimhan H, Pfeifhofer-Obermair C, Schraml B, Hermann-Kleiter N
Front Immunol
. 2025 Jan;
15():1404805.
PMID: 39840064
Nuclear receptors regulate hematopoietic stem cells (HSCs) and peripheral immune cells in mice and humans. The nuclear orphan receptor NR2F6 (EAR-2) has been shown to control murine hematopoiesis. Still, detailed...
3.
Hornsteiner F, Vierthaler J, Strandt H, Resag A, Fu Z, Ausserhofer M, et al.
J Immunother Cancer
. 2024 Apr;
12(4).
PMID: 38631706
Background: Tumor-targeted therapy causes impressive tumor regression, but the emergence of resistance limits long-term survival benefits in patients. Little information is available on the role of the myeloid cell network,...
4.
Schoberleitner I, Faserl K, Tripp C, Pechriggl E, Sigl S, Brunner A, et al.
Front Immunol
. 2024 Apr;
15:1342895.
PMID: 38566997
Excessive fibrous capsule formation around silicone mammary implants (SMI) involves immune reactions to silicone. Capsular fibrosis, a common SMI complication linked to host responses, worsens with specific implant topographies. Our...
5.
Hagen M, Chakraborty T, Olson W, Heitz M, Hermann-Kleiter N, Kimpel J, et al.
Front Immunol
. 2022 Nov;
13:847415.
PMID: 36439112
B lymphocyte development proceeds through a well-ordered sequence of steps, leading to the formation of a sizeable mature B population recognizing a diversity of antigens. These latter cells are ultimately...
6.
Olson W, Jakic B, Labi V, Woelk J, Derudder E, Baier G, et al.
Front Immunol
. 2022 Sep;
13:845235.
PMID: 36052079
B cells are key mediators of humoral immunity. Mature B cells fall into various sub-classes that can be separated by their ontogeny, expression of cell surface markers, anatomical location, and...
7.
Koutnik J, Neururer V, Gruber T, Peer S, Hermann-Kleiter N, Olson W, et al.
Cell Commun Signal
. 2022 Apr;
20(1):54.
PMID: 35440091
Background: The Protein kinase D3 (PKD3) has been implicated in signal transduction downstream of the T cell receptor (TCR). However, its role for the activation of primary T lymphocytes has...
8.
Jakic B, Kimpel J, Olson W, Labi V, Hermann-Kleiter N
Bio Protoc
. 2022 Jan;
11(23):e4247.
PMID: 35005092
Pathogens such as bacteria, viruses, fungi, or protozoa can cause acute and chronic infections in their hosts. The intracellular bacterium serves as a model pathogen to assess the molecular mechanisms...
9.
Jakic B, Olson W, Siegmund K, Klepsch V, Kimpel J, Labi V, et al.
Cell Death Dis
. 2021 Feb;
12(2):187.
PMID: 33589606
Memory formation is a hallmark of T cell-mediated immunity, but how differentiation into either short-lived effector cells (SLECs, CD127KLRG1) or memory precursors cells (MPECs, CD127KLRG1) and subsequent regulation of long-term...
10.
Tymoszuk P, Nairz M, Brigo N, Petzer V, Heeke S, Kircher B, et al.
Front Oncol
. 2020 Dec;
10:584477.
PMID: 33344239
Iron is both, an essential compound for many metabolic processes, and iron deficiency can impact on the proliferation of cells including lymphocytes but also tumor cells. On the other hand,...