William J Olson
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Explore the profile of William J Olson including associated specialties, affiliations and a list of published articles.
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10
Citations
86
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Recent Articles
1.
Olson W, Derudder E
Immunol Lett
. 2023 Jul;
261:37-46.
PMID: 37459958
Immunity in a naïve organism is tightly controlled. Adequate proportions of the many immune cell subsets must be produced to mount efficient responses to eventual challenges. In addition, a functioning...
2.
Hagen M, Chakraborty T, Olson W, Heitz M, Hermann-Kleiter N, Kimpel J, et al.
Front Immunol
. 2022 Nov;
13:847415.
PMID: 36439112
B lymphocyte development proceeds through a well-ordered sequence of steps, leading to the formation of a sizeable mature B population recognizing a diversity of antigens. These latter cells are ultimately...
3.
Olson W, Jakic B, Labi V, Woelk J, Derudder E, Baier G, et al.
Front Immunol
. 2022 Sep;
13:845235.
PMID: 36052079
B cells are key mediators of humoral immunity. Mature B cells fall into various sub-classes that can be separated by their ontogeny, expression of cell surface markers, anatomical location, and...
4.
Koutnik J, Neururer V, Gruber T, Peer S, Hermann-Kleiter N, Olson W, et al.
Cell Commun Signal
. 2022 Apr;
20(1):54.
PMID: 35440091
Background: The Protein kinase D3 (PKD3) has been implicated in signal transduction downstream of the T cell receptor (TCR). However, its role for the activation of primary T lymphocytes has...
5.
Jakic B, Kimpel J, Olson W, Labi V, Hermann-Kleiter N
Bio Protoc
. 2022 Jan;
11(23):e4247.
PMID: 35005092
Pathogens such as bacteria, viruses, fungi, or protozoa can cause acute and chronic infections in their hosts. The intracellular bacterium serves as a model pathogen to assess the molecular mechanisms...
6.
Jakic B, Olson W, Siegmund K, Klepsch V, Kimpel J, Labi V, et al.
Cell Death Dis
. 2021 Feb;
12(2):187.
PMID: 33589606
Memory formation is a hallmark of T cell-mediated immunity, but how differentiation into either short-lived effector cells (SLECs, CD127KLRG1) or memory precursors cells (MPECs, CD127KLRG1) and subsequent regulation of long-term...
7.
Olson W, Martorelli di Genova B, Gallego-Lopez G, Dawson A, Stevenson D, Amador-Noguez D, et al.
PLoS Pathog
. 2020 Apr;
16(4):e1008432.
PMID: 32255806
The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T. gondii manipulates host metabolism to support...
8.
Olson W, Jakic B, Hermann-Kleiter N
FEBS J
. 2020 Apr;
287(14):2866-2890.
PMID: 32246891
The immune system plays an essential role in protecting the host from infectious diseases and cancer. Notably, B and T lymphocytes from the adaptive arm of the immune system can...
9.
Olson W, Jakic B, Labi V, Schoeler K, Kind M, Klepsch V, et al.
Cell Rep
. 2019 Sep;
28(11):2878-2891.e5.
PMID: 31509749
CD4 T follicular helper (Tfh) cells are specialized in helping B cells during the germinal center (GC) reaction and ultimately promote long-term humoral immunity. Here we report that loss of...
10.
Klepsch V, Gerner R, Klepsch S, Olson W, Tilg H, Moschen A, et al.
Gut
. 2017 Aug;
67(8):1434-1444.
PMID: 28779026
Objective: Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory...