Naroa Insausti-Urkia
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Explore the profile of Naroa Insausti-Urkia including associated specialties, affiliations and a list of published articles.
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6
Citations
115
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Recent Articles
1.
Fucho R, Solsona-Vilarrasa E, Torres S, Nunez S, Insausti-Urkia N, Edo A, et al.
J Lipid Res
. 2023 Jul;
64(8):100413.
PMID: 37473919
Alcoholic-related liver disease (ALD) is one of the leading causes of chronic liver disease and morbidity. Unfortunately, the pathogenesis of ALD is still incompletely understood. StARD1 has emerged as a...
2.
Alarcon-Vila C, Insausti-Urkia N, Torres S, Segales-Rovira P, Conde de la Rosa L, Nunez S, et al.
Redox Biol
. 2023 Jan;
59:102596.
PMID: 36610223
Alcoholic (ASH) and nonalcoholic. (NASH).steatohepatitis are advanced.stages.of.fatty.liver.disease.Methionine adenosyltransferase 1A (MAT1A) plays a key role in hepatic methionine metabolism and germline Mat1a deletion in mice promotes NASH. Acid sphingomyelinase (ASMase) triggers...
3.
Ribas V, Conde de la Rosa L, Robles D, Nunez S, Segales P, Insausti-Urkia N, et al.
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439245
The association of nonalcoholic steatohepatitis (NASH) with obesity and type 2 diabetes is a major determinant factor for the continued rise of NASH-driven HCC. Unfortunately, the mechanisms underlying the progression...
4.
Torres S, Solsona-Vilarrasa E, Nunez S, Matias N, Insausti-Urkia N, Castro F, et al.
Redox Biol
. 2021 Jun;
45:102052.
PMID: 34175669
Niemann-Pick type C (NPC) disease, a lysosomal storage disorder caused by defective NPC1/NPC2 function, results in the accumulation of cholesterol and glycosphingolipids in lysosomes of affected organs, such as liver...
5.
Insausti-Urkia N, Solsona-Vilarrasa E, Garcia-Ruiz C, Fernandez-Checa J
Biomolecules
. 2020 Nov;
10(11).
PMID: 33143193
Sphingolipids (SLs) are critical components of membrane bilayers that play a crucial role in their physico-chemical properties. Ceramide is the prototype and most studied SL due to its role as...
6.
Torres S, Baulies A, Insausti-Urkia N, Alarcon-Vila C, Fucho R, Solsona-Vilarrasa E, et al.
Gastroenterology
. 2019 Apr;
157(2):552-568.
PMID: 31029706
Background & Aims: Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). Mitochondrial SH3BP5 (also called SAB) and phosphorylation of c-Jun N-terminal kinase (JNK) mediate the hepatotoxic...