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Estel Solsona-Vilarrasa

Explore the profile of Estel Solsona-Vilarrasa including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 238
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Recent Articles
1.
Solsona-Vilarrasa E, Vousden K
FEBS J . 2024 Nov; PMID: 39496581
White adipose tissue (WAT) is crucial for whole-body energy homeostasis and plays an important role in metabolic and hormonal regulation. While healthy WAT undergoes controlled expansion and contraction to meet...
2.
Fucho R, Solsona-Vilarrasa E, Torres S, Nunez S, Insausti-Urkia N, Edo A, et al.
J Lipid Res . 2023 Jul; 64(8):100413. PMID: 37473919
Alcoholic-related liver disease (ALD) is one of the leading causes of chronic liver disease and morbidity. Unfortunately, the pathogenesis of ALD is still incompletely understood. StARD1 has emerged as a...
3.
Cordoba-Jover B, Ribera J, Portoles I, Lecue E, Rodriguez-Vita J, Perez-Sisques L, et al.
Liver Int . 2023 Jun; 43(8):1822-1836. PMID: 37312667
Background & Aims: Transcription co-activator factor 20 (TCF20) is a regulator of transcription factors involved in extracellular matrix remodelling. In addition, TCF20 genomic variants in humans have been associated with...
4.
Canto-Santos J, Valls-Roca L, Tobias E, Garcia-Garcia F, Guitart-Mampel M, Esteve-Codina A, et al.
J Cachexia Sarcopenia Muscle . 2023 Mar; 14(2):964-977. PMID: 36860172
Background: Inclusion body myositis (IBM) is an inflammatory myopathy clinically characterized by proximal and distal muscle weakness, with inflammatory infiltrates, rimmed vacuoles and mitochondrial changes in muscle histopathology. There is...
5.
Ribera J, Portoles I, Cordoba-Jover B, Rodriguez-Vita J, Casals G, Gonzalez-de la Presa B, et al.
Commun Biol . 2021 Oct; 4(1):1192. PMID: 34654883
DHX15 is a downstream substrate for Akt1, which is involved in key cellular processes affecting vascular biology. Here, we explored the vascular regulatory function of DHX15. Homozygous DHX15 gene deficiency...
6.
Ribas V, Conde de la Rosa L, Robles D, Nunez S, Segales P, Insausti-Urkia N, et al.
Cancers (Basel) . 2021 Aug; 13(16). PMID: 34439245
The association of nonalcoholic steatohepatitis (NASH) with obesity and type 2 diabetes is a major determinant factor for the continued rise of NASH-driven HCC. Unfortunately, the mechanisms underlying the progression...
7.
Torres S, Solsona-Vilarrasa E, Nunez S, Matias N, Insausti-Urkia N, Castro F, et al.
Redox Biol . 2021 Jun; 45:102052. PMID: 34175669
Niemann-Pick type C (NPC) disease, a lysosomal storage disorder caused by defective NPC1/NPC2 function, results in the accumulation of cholesterol and glycosphingolipids in lysosomes of affected organs, such as liver...
8.
Koh E, Yoon J, Ko M, Leem J, Yun J, Hong C, et al.
Gut . 2020 Nov; 70(10):1954-1964. PMID: 33208407
Objective: Lipotoxic hepatocyte injury is a primary event in non-alcoholic steatohepatitis (NASH), but the mechanisms of lipotoxicity are not fully defined. Sphingolipids and free cholesterol (FC) mediate hepatocyte injury, but...
9.
Insausti-Urkia N, Solsona-Vilarrasa E, Garcia-Ruiz C, Fernandez-Checa J
Biomolecules . 2020 Nov; 10(11). PMID: 33143193
Sphingolipids (SLs) are critical components of membrane bilayers that play a crucial role in their physico-chemical properties. Ceramide is the prototype and most studied SL due to its role as...
10.
Solsona-Vilarrasa E, Fucho R, Torres S, Nunez S, Nuno-Lambarri N, Enrich C, et al.
Redox Biol . 2019 May; 24:101214. PMID: 31108462
Mitochondrial cholesterol accumulation is a hallmark of alcoholic and non-alcoholic fatty liver diseases and impairs the function of specific solute carriers through changes in membrane physical properties. However, its impact...