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Nanna Grand

Explore the profile of Nanna Grand including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 77
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Recent Articles
1.
Grand N, Jeppesen G, Nyska A
Toxicol Pathol . 2024 Oct; 52(6):350-352. PMID: 39417580
Minipigs are valued alternatives to dogs and non-human primates in non-clinical safety and toxicity studies, and Göttingen minipigs are bred specifically for experimental purposes. They are bred under barrier conditions...
2.
Jhelum H, Grand N, Jacobsen K, Halecker S, Salerno M, Prate R, et al.
PLoS One . 2023 Jun; 18(6):e0281521. PMID: 37319233
Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red,...
3.
Haagensen A, Grand N, Klastrup S, Skytte C, Sorensen D
Behav Pharmacol . 2013 Apr; 24(3):172-9. PMID: 23542905
Two methods investigating learning and memory in juvenile Göttingen minipigs were evaluated for potential use in preclinical toxicity testing. Twelve minipigs were tested using a spatial hole-board discrimination test including...
4.
Ellegaard L, Cunningham A, Edwards S, Grand N, Nevalainen T, Prescott M, et al.
J Pharmacol Toxicol Methods . 2010 Jul; 62(3):167-83. PMID: 20621655
This paper reviews the animal welfare challenges associated with the use of minipigs in toxicology testing, and compares these to published knowledge on the other widely used non-rodent species (dogs...
5.
Christoffersen B, Grand N, Golozoubova V, Svendsen O, Raun K
Comp Med . 2007 Nov; 57(5):493-504. PMID: 17974133
Gender-associated differences in pathophysiology and treatment of disease are an evolving area in human medicine that should be addressed in animal models. The aim of this study was to characterize...
6.
Jelsing J, Nielsen R, Olsen A, Grand N, Hemmingsen R, Pakkenberg B
J Exp Biol . 2006 Apr; 209(Pt 8):1454-62. PMID: 16574805
The first mathematically unbiased estimates of neocortical cell numbers are presented from the developing pig brain, including a full description of tissue processing and optimal sampling for application of the...