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Nadiya Orel

Explore the profile of Nadiya Orel including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 259
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Recent Articles
1.
Colangelo P, Di Civita M, Bento C, Franchini P, Meyer A, Orel N, et al.
BMC Ecol Evol . 2024 Mar; 24(1):29. PMID: 38433185
The African buffalo, Syncerus caffer, is a key species in African ecosystems. Like other large herbivores, it plays a fundamental role in its habitat acting as an ecosystem engineer. Over...
2.
Groh J, Friedman H, Orel N, Ip C, Fischer S, Spahn I, et al.
Hum Mol Genet . 2017 Feb; 25(21):4686-4702. PMID: 28173160
Progressive forms of multiple sclerosis lead to chronic disability, substantial decline in quality of life and reduced longevity. It is often suggested that they occur independently of inflammation. Here we...
3.
Puehringer D, Orel N, Luningschror P, Subramanian N, Herrmann T, Chao M, et al.
Nat Neurosci . 2013 Feb; 16(4):407-15. PMID: 23416450
The development of neuronal networks in the neocortex depends on control mechanisms for mitosis and migration that allow newborn neurons to find their accurate position. Multiple mitogens, neurotrophic factors, guidance...
4.
Chen I, Mannuss A, Orel N, Heitzeberg F, Puchta H
Plant Physiol . 2008 Mar; 146(4):1786-96. PMID: 18310306
Rad5 is the key component in the Rad5-dependent error-free branch of postreplication repair in yeast (Saccharomyces cerevisiae). Rad5 is a member of the Snf2 ATPase/helicase family, possessing as a characteristic...
5.
Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao M, et al.
Proc Natl Acad Sci U S A . 2007 Oct; 104(43):17210-5. PMID: 17940030
Neurotrophins are potent survival factors for developing and injured neurons. However, they are not being used to treat neurodegenerative diseases because of difficulties in administration and numerous side effects that...
6.
Bender F, Fischer M, Funk N, Orel N, Rethwilm A, Sendtner M
Histochem Cell Biol . 2006 Nov; 127(4):439-48. PMID: 17102992
Primary neurons are a common tool for investigating gene function for survival and morphological and functional differentiation. Gene transfer techniques play an important role in this context. However, the efficacy...
7.
Heitzeberg F, Chen I, Hartung F, Orel N, Angelis K, Puchta H
Plant J . 2004 May; 38(6):954-68. PMID: 15165187
Rad17 is involved in DNA checkpoint control in yeast and human cells. A homologue of this gene as well as other genes of the pathway (the 9-1-1 complex) are present...
8.
Schmidt-Puchta W, Orel N, Kyryk A, Puchta H
Methods Mol Biol . 2004 Feb; 262:25-34. PMID: 14769954
Because of the availability of the complete sequence of the genome of the model plant Arabidopsis and of insertion mutants for most genes in public mutant collections, the elucidation of...
9.
Orel N, Kyryk A, Puchta H
Plant J . 2003 Aug; 35(5):604-12. PMID: 12940953
Different DNA repair pathways that use homologous sequences in close proximity to genomic double-strand breaks (DSBs) result in either an internal deletion or a gene conversion. We determined the efficiency...
10.
Orel N, Puchta H
Plant Mol Biol . 2003 Mar; 51(4):523-31. PMID: 12650618
Surprising species-specific differences in non-homologous end-joining (NHEJ) of genomic double-strand breaks (DSBs) have been reported for the two dicotyledonous plants Arabidopsis thaliana and Nicotiana tabacum. In Arabidopsis deletions were, on...