Nadine Spielmann
Overview
Explore the profile of Nadine Spielmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
34
Citations
399
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Raj Murthi S, Petry A, Shashikadze B, Stockl J, Schmid M, Santamaria G, et al.
Sci Rep
. 2025 Jan;
15(1):2132.
PMID: 39820339
Hypertrophic cardiomyopathy (HCM) caused by autosomal-dominant mutations in genes coding for structural sarcomeric proteins, is the most common inherited heart disease. HCM is associated with myocardial hypertrophy, fibrosis and ventricular...
2.
Hasenbein T, Hoelzl S, Smith Z, Gerhardinger C, Gonner M, Aguilar-Pimentel A, et al.
Nat Commun
. 2024 Dec;
15(1):10631.
PMID: 39638999
The lncRNA Crossfirre was identified as an imprinted X-linked gene, and is transcribed antisense to the trans-acting lncRNA Firre. The Firre locus forms an inactive-X-specific interaction with Dxz4, both loci...
3.
Henderson D, Alqahtani A, Chaudhry B, Cook A, Eley L, Houyel L, et al.
Dis Model Mech
. 2024 Nov;
17(11).
PMID: 39575509
Congenital heart defects (CHDs), the most common congenital anomalies, are considered to have a significant genetic component. However, despite considerable efforts to identify pathogenic genes in patients with CHDs, few...
4.
Spielmann N, Miller G, Oprea T, Hsu C, Fobo G, Frishman G, et al.
Nat Cardiovasc Res
. 2024 Aug;
1(2):157-173.
PMID: 39195995
Clinical presentation of congenital heart disease is heterogeneous, making identification of the disease-causing genes and their genetic pathways and mechanisms of action challenging. By using in vivo electrocardiography, transthoracic echocardiography...
5.
Hones G, Geist D, Wenzek C, Pfluger P, Muller T, Aguilar-Pimentel J, et al.
Endocrinology
. 2024 Jun;
165(8).
PMID: 38889231
Thyroid hormone (TH) effects are mediated through TH receptors (TRs), TRα1, TRβ1, and TRβ2. The TRs bind to the DNA and regulate expression of TH target genes (canonical signaling). In...
6.
Geist D, Hones G, Grund S, Pape J, Siemes D, Spangenberg P, et al.
Thyroid
. 2024 May;
34(6):785-795.
PMID: 38757582
Stimulation of ventricular hypertrophy and heart rate are two major cardiac effects of thyroid hormone (TH). The aim of this study was to determine which TH receptor (TR)-α or β-and...
7.
Tollot-Wegner M, Jessen M, Kim K, Sanz-Moreno A, Spielmann N, Gailus-Durner V, et al.
Breast Cancer Res
. 2024 May;
26(1):74.
PMID: 38702730
The transcription factor TRPS1 is a context-dependent oncogene in breast cancer. In the mammary gland, TRPS1 activity is restricted to the luminal population and is critical during puberty and pregnancy....
8.
Huang X, Henck J, Qiu C, Sreenivasan V, Balachandran S, Amarie O, et al.
Nature
. 2023 Nov;
623(7988):772-781.
PMID: 37968388
Mouse models are a critical tool for studying human diseases, particularly developmental disorders. However, conventional approaches for phenotyping may fail to detect subtle defects throughout the developing mouse. Here we...
9.
Lindovsky J, Nichtova Z, Dragano N, Reguera D, Prochazka J, Fuchs H, et al.
Mamm Genome
. 2023 Jun;
34(2):107-122.
PMID: 37326672
Cardiovascular diseases cause a high mortality rate worldwide and represent a major burden for health care systems. Experimental rodent models play a central role in cardiovascular disease research by effectively...
10.
Oestereicher M, Wotton J, Ayabe S, Bou About G, Cheng T, Choi J, et al.
Mamm Genome
. 2023 Jun;
34(2):180-199.
PMID: 37294348
Reference ranges provide a powerful tool for diagnostic decision-making in clinical medicine and are enormously valuable for understanding normality in pre-clinical scientific research that uses in vivo models. As yet,...