Nadia P Belichenko
Overview
Explore the profile of Nadia P Belichenko including associated specialties, affiliations and a list of published articles.
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14
Citations
700
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0
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Recent Articles
1.
Simmons D, Belichenko N, Longo F
J Huntingtons Dis
. 2023 Aug;
12(3):215-239.
PMID: 37638447
Background: Loss of neurotrophic support in the striatum, particularly reduced brain-derived neurotrophic factor (BDNF) levels, contributes importantly to Huntington's disease (HD) pathogenesis. Another neurotrophin (NT), NT-3, is reduced in the...
2.
Nguyen T, Hayes M, Zbesko J, Frye J, Congrove N, Belichenko N, et al.
Acta Neuropathol Commun
. 2018 Sep;
6(1):100.
PMID: 30249297
The goal of this study was to determine the chronic impact of stroke on the manifestation of Alzheimer's disease (AD) related pathology and behavioral impairments in mice. To accomplish this...
3.
Simmons D, James M, Belichenko N, Semaan S, Condon C, Kuan J, et al.
Hum Mol Genet
. 2018 Jun;
27(16):2893-2912.
PMID: 29860333
Huntington's disease (HD) is an inherited neurodegenerative disorder that has no cure. HD therapeutic development would benefit from a non-invasive translatable biomarker to track disease progression and treatment response. A...
4.
James M, Belichenko N, Shuhendler A, Hoehne A, Andrews L, Condon C, et al.
Theranostics
. 2017 May;
7(6):1422-1436.
PMID: 28529627
Microglial activation is a key pathological feature of Alzheimer's disease (AD). PET imaging of translocator protein 18 kDa (TSPO) is a strategy to detect microglial activation . Here we assessed...
5.
Czirr E, Castello N, Mosher K, Castellano J, Hinkson I, Lucin K, et al.
J Exp Med
. 2017 Mar;
214(4):1081-1092.
PMID: 28298456
Recent genetic evidence supports a link between microglia and the complement system in Alzheimer's disease (AD). In this study, we uncovered a novel role for the microglial complement receptor 3...
6.
Simmons D, Belichenko N, Ford E, Semaan S, Monbureau M, Aiyaswamy S, et al.
Hum Mol Genet
. 2017 Feb;
25(22):4920-4938.
PMID: 28171570
Decreases in the ratio of neurotrophic versus neurodegenerative signalling play a critical role in Huntington’s disease (HD) pathogenesis and recent evidence suggests that the p75 neurotrophin receptor (NTR) contributes significantly...
7.
James M, Belichenko N, Nguyen T, Andrews L, Ding Z, Liu H, et al.
J Nucl Med
. 2015 Jan;
56(2):311-6.
PMID: 25613536
Unlabelled: Herein we aimed to evaluate the utility of N-(2,5-dimethoxybenzyl)-2-(18)F-fluoro-N-(2-phenoxyphenyl)acetamide ((18)F-PBR06) for detecting alterations in translocator protein (TSPO) (18 kDa), a biomarker of microglial activation, in a mouse model of...
8.
Simmons D, Knowles J, Belichenko N, Banerjee G, Finkle C, Massa S, et al.
PLoS One
. 2014 Aug;
9(8):e102136.
PMID: 25153701
Degeneration of basal forebrain cholinergic neurons contributes significantly to the cognitive deficits associated with Alzheimer's disease (AD) and has been attributed to aberrant signaling through the neurotrophin receptor p75 (p75NTR)....
9.
Nguyen T, Shen L, Vander Griend L, Quach L, Belichenko N, Saw N, et al.
J Alzheimers Dis
. 2014 Jun;
42(2):459-83.
PMID: 24898660
The p75 neurotrophin receptor (p75NTR) is involved in degenerative mechanisms related to Alzheimer's disease (AD). In addition, p75NTR levels are increased in AD and the receptor is expressed by neurons...
10.
Simmons D, Belichenko N, Yang T, Condon C, Monbureau M, Shamloo M, et al.
J Neurosci
. 2013 Nov;
33(48):18712-27.
PMID: 24285878
Loss of neurotrophic support in the striatum caused by reduced brain-derived neurotrophic factor (BDNF) levels plays a critical role in Huntington's disease (HD) pathogenesis. BDNF acts via TrkB and p75...