N van Rooijen
Overview
Explore the profile of N van Rooijen including associated specialties, affiliations and a list of published articles.
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334
Citations
7405
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Recent Articles
1.
van Leeuwen M, Costes L, van Berkel L, Simons-Oosterhuis Y, du Pre M, Kozijn A, et al.
Mucosal Immunol
. 2016 Sep;
10(3):635-649.
PMID: 27579860
Celiac disease is caused by inflammatory T-cell responses against the insoluble dietary protein gliadin. We have shown that, in humanized mice, oral tolerance to deamidated chymotrypsin-digested gliadin (CT-TG2-gliadin) is driven...
2.
Hitchcock J, Cook C, Bobat S, Ross E, Flores-Langarica A, Lowe K, et al.
J Clin Invest
. 2015 Nov;
125(12):4429-46.
PMID: 26571395
Thrombosis is a common, life-threatening consequence of systemic infection; however, the underlying mechanisms that drive the formation of infection-associated thrombi are poorly understood. Here, using a mouse model of systemic...
3.
Rawley O, OSullivan J, Chion A, Keyes S, Lavin M, van Rooijen N, et al.
J Thromb Haemost
. 2015 Feb;
13(5):821-6.
PMID: 25690668
Background: Enhanced von Willebrand factor (VWF) clearance is important in the etiology of type 1 and type 2 von Willebrand disease (VWD). More than 20 different VWF point mutations have...
4.
van Rooijen N, Claassen E, Eikelenboom P
Immunol Today
. 2014 Oct;
7(7-8):193-6.
PMID: 25290395
By incubating tissue sections with antigen (or hapten)-enzyme conjugates, followed by enzyme cytochemistry(1-4), N. van Rooijen and his colleagues have been able to study the development and localization of specific...
5.
Narasaraju T, Yang E, Samy R, Tan K, Moorthy A, Phoon M, et al.
Curr Mol Med
. 2014 Jun;
14(5):690-702.
PMID: 24894172
Frequent outbreaks caused by influenza viruses pose considerable public health threats worldwide. Virus-inflicted alveolar damage represents a major contributor of acute lung injury in influenza. We have previously demonstrated that...
6.
Partecke L, Gunther C, Hagemann S, Jacobi C, Merkel M, Sendler M, et al.
Pancreatology
. 2013 Oct;
13(5):508-16.
PMID: 24075516
Introduction: More effective therapies are required to improve survival of pancreatic cancer. Possible immunologic targets include tumour associated macrophages (TAMs), generally consisting of M1- and M2-macrophages. We have analysed the...
7.
Zhou Z, Sharma V, Beaty B, Roh-Johnson M, Peterson E, van Rooijen N, et al.
Oncogene
. 2013 Sep;
33(29):3784-93.
PMID: 24013225
Increased expression of HBEGF in estrogen receptor-negative breast tumors is correlated with enhanced metastasis to distant organ sites and more rapid disease recurrence upon removal of the primary tumor. Our...
8.
Kruse J, von Bernstorff W, Evert K, Albers N, Hadlich S, Hagemann S, et al.
Int J Colorectal Dis
. 2013 May;
28(10):1337-49.
PMID: 23657400
Purpose: Tumour-associated macrophages have been shown to promote proliferation, angiogenesis and metastasis in several carcinomas. The effect on colon cancer has not yet been clarified. Furthermore, Kupffer cells in the...
9.
Al-Anati L, Reinehr R, van Rooijen N, Petzinger E
Mycotoxin Res
. 2013 Apr;
21(3):172-5.
PMID: 23605335
Tumor necrosis factor-α (TNF-α) is released from blood-free perfused rat liver by the fungal metabolite ochratoxin A. Here we have identified Kupffer cells as the sole source of OTA-mediated cytokine...
10.
Coughlan L, Vallath S, Gros A, Gimenez-Alejandre M, van Rooijen N, Thomas G, et al.
Hum Gene Ther
. 2012 Jun;
23(9):960-79.
PMID: 22708837
Achieving high-efficiency tumor targeting after systemic delivery is a considerable challenge facing oncolytic gene therapists. Efficient retargeting should be combined with efforts to improve in vivo safety, reduce hepatotoxicity, minimize...