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N Noraz

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Articles 18
Citations 285
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Recent Articles
1.
Dardalhon V, Jaleco S, Kinet S, Herpers B, Steinberg M, Ferrand C, et al.
Proc Natl Acad Sci U S A . 2001 Jul; 98(16):9277-82. PMID: 11470908
Differences in the immunological reactivity of umbilical cord (UC) and adult peripheral blood (APB) T cells are poorly understood. Here, we show that IL-7, a cytokine involved in lymphoid homeostasis,...
2.
Dardalhon V, Herpers B, Noraz N, Pflumio F, Guetard D, Leveau C, et al.
Gene Ther . 2001 Apr; 8(3):190-8. PMID: 11313790
Retroviral vectors have become the primary tool for gene delivery into hematopoietic cells, including T lymphocytes. Lentiviral vectors offer an advantage over Moloney murine leukemia virus (MuLV) vectors because of...
3.
Ferlin M, Noraz N, Hertogh C, BROCHIER J, Taylor N, Klein B
Br J Haematol . 2000 Dec; 111(2):626-34. PMID: 11122111
Multiple myeloma (MM) is a B-cell neoplasia that is associated with an increased level of bone resorption. One important mediator of bone remodelling, insulin-like growth factor (IGF-I), has been shown...
4.
Steinberg M, Swainson L, Schwarz K, Boyer M, Friedrich W, Yssel H, et al.
Gene Ther . 2000 Sep; 7(16):1392-400. PMID: 10981666
Humans lacking the ZAP-70 protein tyrosine kinase present with an absence of CD8+ T cells and defective CD4+ T cells in the periphery. This severe combined immunodeficiency is fatal unless...
5.
Dardalhon V, Jaleco S, Rebouissou C, Ferrand C, Skander N, Swainson L, et al.
Blood . 2000 Jul; 96(3):885-93. PMID: 10910901
Retroviral vectors based on the Moloney murine leukemia virus (MuLV) have become the primary tool for gene delivery into hematopoietic cells, but clinical trials have been hampered by low transduction...
6.
Noraz N, Schwarz K, Steinberg M, Dardalhon V, Rebouissou C, Hipskind R, et al.
J Biol Chem . 2000 Apr; 275(21):15832-8. PMID: 10748099
ZAP-70-deficient patients present with nonfunctional CD4+ T cells in the periphery. We find that a subset of primary ZAP-70-deficient T cells, expressing high levels of the related protein-tyrosine kinase Syk,...
7.
Misse D, Cerutti M, Noraz N, Jourdan P, Favero J, Devauchelle G, et al.
Blood . 1999 Apr; 93(8):2454-62. PMID: 10194422
The gp120 envelope glycoprotein of human immunodeficiency virus-1 (HIV-1) interacts with the CXCR4 chemokine receptor, but it is not known whether gp120 activates CXCR4-mediated signaling cascades in the same manner...
8.
Dardalhon V, Noraz N, Pollok K, Rebouissou C, Boyer M, Bakker A, et al.
Hum Gene Ther . 1999 Feb; 10(1):5-14. PMID: 10022526
The success of gene therapy strategies for congenital and acquired blood disorders requires high levels of gene transfer into hematopoietic cells. Retroviral vectors have been extensively used to deliver foreign...
9.
Goldman F, Ballas Z, Schutte B, Kemp J, Hollenback C, Noraz N, et al.
J Clin Invest . 1998 Jul; 102(2):421-9. PMID: 9664084
Severe combined immune deficiency (SCID) is a heterogeneous disorder characterized by profound defects in cellular and humoral immunity. We report here an infant with clinical and laboratory features of SCID...
10.
Jourdan P, Abbal C, Noraz N, Hori T, Uchiyama T, Vendrell J, et al.
J Immunol . 1998 May; 160(9):4153-7. PMID: 9574513
Here we report that IL-4 specifically enhances cell surface expression of CXCR4 on resting peripheral and cord blood T cells. Whereas polarized Th2 clones express variable levels of CXCR4, expression...