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N L Cacheiro

Explore the profile of N L Cacheiro including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Alagramam K, Kwon H, Cacheiro N, Stubbs L, Wright C, Erway L, et al.
Genetics . 1999 Aug; 152(4):1691-9. PMID: 10430593
This article describes a new recessive insertional mutation in the transgenic line TgN2742Rpw that causes deafness and circling behavior in mice. Histologic analysis revealed virtually complete loss of the cochlear...
2.
Stubbs L, Carver E, Cacheiro N, Shelby M, Generoso W
Methods . 1998 Mar; 13(4):397-408. PMID: 9480784
Reciprocal translocations have provided crucial tools for the localization of genes associated with a variety of human cancers and hereditary diseases. Although heritable translocations are relatively rare in humans, they...
3.
Culiat C, Carver E, Walkowicz M, Rinchik E, Cacheiro N, Russell L, et al.
Reprod Toxicol . 1997 Mar; 11(2-3):345-51. PMID: 9100310
Due to the rapid advances that have been made in molecular and genetic technology during the past decade, the genes associated with a large number of human hereditary diseases have...
4.
Generoso W, Sega G, Lockhart A, Hughes L, Cain K, Cacheiro N, et al.
Mutat Res . 1996 Dec; 371(3-4):175-83. PMID: 9008719
The hypothesis that acrylamide induces dominant lethal mutations and heritable translocations in male mice, not through direct adduction, but by conversion to the reactive epoxide, glycidamide, was investigated. Three studies,...
5.
Russell L, Montgomery C, Cacheiro N, Johnson D
Genetics . 1995 Dec; 141(4):1547-62. PMID: 8601493
The homozygous and heterozygous phenotypes are described and characterized for 45 new pink-eyed dilution (p) locus mutations, most of them radiation-induced, that affect survival at various stages of mouse development....
6.
Generoso W, Witt K, Cain K, Hughes L, Cacheiro N, Lockhart A, et al.
Mutat Res . 1995 Dec; 345(3-4):167-80. PMID: 8552138
Chemicals used in the treatment of cancer include several that are potent mutagens in a range of in vitro and in vivo assays. For some, genetic effects have also been...
7.
Moyer J, Kwon H, Schrick J, Avner E, Sweeney W, Godfrey V, et al.
Science . 1994 May; 264(5163):1329-33. PMID: 8191288
A line of transgenic mice was generated that contains an insertional mutation causing a phenotype similar to human autosomal recessive polycystic kidney disease. Homozygotes displayed a complex phenotype that included...
8.
Cacheiro N, Rutledge J, Cain K, Cornett C, Generoso W
Cytogenet Cell Genet . 1994 Jan; 66(2):139-48. PMID: 8287687
Reciprocal translocations are readily induced by various physical and chemical mutagens in certain germ-cell stages. Carriers of balanced reciprocal translocations generally exhibit no abnormal phenotypes, except for occasional male sterility,...
9.
Ashley T, Cacheiro N, Russell L, Ward D
Chromosoma . 1993 Jan; 102(2):112-20. PMID: 8432192
A "hot spot" of meiotic recombination has been found in males on murine chromosome 8 using nonisotopic hybridization of a series of probes to mitotic and meiotic chromosomes. The sequences...
10.
Russell L, Hunsicker P, Cacheiro N, Rinchik E
Proc Natl Acad Sci U S A . 1992 Jul; 89(13):6182-6. PMID: 1352884
Specific-locus experiments have previously shown melphalan to be mutagenic in all male germ-cell stages tested and particularly so in early spermatids. All but 2 of 24 specific-locus mutations recovered were...