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N F Voelkel

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Articles 197
Citations 5193
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Recent Articles
1.
Happe C, de Raaf M, Rol N, Schalij I, Vonk-Noordegraaf A, Westerhof N, et al.
Am J Physiol Lung Cell Mol Physiol . 2016 Apr; 310(11):L1088-97. PMID: 27036867
The SU5416 + hypoxia (SuHx) rat model is a commonly used model of severe pulmonary arterial hypertension. While it is known that exposure to hypoxia can be replaced by another...
2.
Happe C, Szulcek R, Voelkel N, Bogaard H
Vascul Pharmacol . 2016 Jan; 83:17-25. PMID: 26804008
In pulmonary arterial hypertension (PAH) structural and functional abnormalities of the small lung vessels interact and lead to a progressive increase in pulmonary vascular resistance and right heart failure. A...
3.
Voelkel N, Gomez-Arroyo J
Int J Clin Pract Suppl . 2011 Jul; (172):1-2. PMID: 21736674
No abstract available.
4.
Yasuo M, Mizuno S, Kraskauskas D, Bogaard H, Natarajan R, Cool C, et al.
Eur Respir J . 2010 Jun; 37(4):775-83. PMID: 20562128
The pathobiology of chronic obstructive pulmonary disease (COPD) is not completely understood. The aim of this study was to assess the expression of hypoxia inducible factor (HIF)-1α in lung tissue...
5.
Chen Y, Hanaoka M, Droma Y, Chen P, Voelkel N, Kubo K
Eur Respir J . 2009 Nov; 35(4):904-12. PMID: 19897563
We hypothesised that endothelin (ET)-1 plays an important role in the pathogenesis of emphysema. We attempted to apply ET-1 receptor antagonists to demonstrate and further elucidate the molecular pathogenesis pathways...
6.
Koff P, Jones R, Cashman J, Voelkel N, Vandivier R
Eur Respir J . 2009 Jan; 33(5):1031-8. PMID: 19129289
Self-management strategies improve a variety of health-related outcomes for patients with chronic obstructive pulmonary disease (COPD). These strategies, however, are primarily designed to improve chronic disease management and have not...
7.
Golpon H, Voelkel N
Curr Drug Targets . 2006 Jun; 7(6):737-41. PMID: 16787175
Pulmonary emphysema, a major component of chronic obstructive pulmonary diseases, is a highly prevalent progressive tissue-destructive disease, with no effective treatments. The interplay between inflammation, matrix proteolysis, oxidative stress and...
8.
Nicolls M, Taraseviciene-Stewart L, Rai P, Badesch D, Voelkel N
Eur Respir J . 2005 Dec; 26(6):1110-8. PMID: 16319344
The association between autoimmunity and pulmonary arterial hypertension (PAH) has been appreciated for >40 yrs, but how autoimmune injury might contribute to the pathogenesis of this disease has only been...
9.
Voelkel N, Agusti A
Pulm Pharmacol Ther . 2004 Oct; 17(5):249-51. PMID: 15477119
No abstract available.
10.
Voelkel N, Cool C
Eur Respir J Suppl . 2003 Nov; 46:28s-32s. PMID: 14621104
Chronic obstructive lung disease affects the entire lung, not just the airways. Although pulmonary hypertension (PH) has long been recognised in a subset of patients with COLD, the important pathophysiological...