N F Voelkel
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Explore the profile of N F Voelkel including associated specialties, affiliations and a list of published articles.
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197
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5193
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Recent Articles
11.
Bull T, Cool C, Serls A, Rai P, Parr J, Neid J, et al.
Eur Respir J
. 2003 Oct;
22(3):403-7.
PMID: 14516126
Primary pulmonary hypertension (PPH) and Castleman's disease (CD) are rare conditions infrequently encountered in clinical practice. In this paper, two patients diagnosed with both of these diseases are reported. The...
12.
Geraci M, Gao B, Hoshikawa Y, Yeager M, Tuder R, Voelkel N
Respir Res
. 2001 Nov;
2(4):210-5.
PMID: 11686886
Genomics, or the study of genes and their function, is a burgeoning field with many new technologies. In the present review, we explore the application of genomic approaches to the...
13.
Tuder R, Chacon M, Alger L, Wang J, Taraseviciene-Stewart L, Kasahara Y, et al.
J Pathol
. 2001 Oct;
195(3):367-74.
PMID: 11673836
Pulmonary arteries of patients with severe pulmonary hypertension (SPH) presenting in an idiopathic form (primary PH-PPH) or associated with congenital heart malformations or collagen vascular diseases show plexiform lesions. It...
14.
Tuder R, Cool C, Yeager M, Taraseviciene-Stewart L, Bull T, Voelkel N
Clin Chest Med
. 2001 Oct;
22(3):405-18.
PMID: 11590837
Dysfunctional endothelial cells have a central and critical role in the initiation and progression of severe pulmonary hypertension. The elucidation of the mechanisms involved in the control of endothelial cell...
15.
Tuder R, Yeager M, Geraci M, Golpon H, Voelkel N
Eur Respir J
. 2001 Aug;
17(6):1065-9.
PMID: 11491145
The recent discoveries of the familial primary pulmonary hypertension gene and somatic mutations in key cell growth and cell death regulatory genes in primary pulmonary hypertension have added a new...
16.
Hoshikawa Y, Voelkel N, Gesell T, Moore M, Morris K, Alger L, et al.
Am J Respir Crit Care Med
. 2001 Jul;
164(2):314-8.
PMID: 11463607
Prostacyclin (PGI(2)) reduces pulmonary vascular resistance and attenuates vascular smooth muscle cell proliferation through signal transduction following ligand binding to its receptor. Because patients with severe pulmonary hypertension have a...
17.
18.
Geraci M, Moore M, Gesell T, Yeager M, Alger L, Golpon H, et al.
Circ Res
. 2001 Apr;
88(6):555-62.
PMID: 11282888
Primary pulmonary hypertension (PPH) is a disease of unknown etiology characterized by lumen-obliterating endothelial cell proliferation and vascular smooth muscle hypertrophy of the small precapillary pulmonary arteries. Because the vascular...
19.
Kasahara Y, Tuder R, Cool C, Lynch D, Flores S, Voelkel N
Am J Respir Crit Care Med
. 2001 Mar;
163(3 Pt 1):737-44.
PMID: 11254533
Emphysema due to cigarette smoking is characterized by a loss of alveolar structures. We hypothesize that the disappearance of alveoli involves apoptosis of septal endothelial cells and a decreased expression...
20.
Hoshikawa Y, Ono S, Suzuki S, Tanita T, Chida M, Song C, et al.
J Appl Physiol (1985)
. 2001 Mar;
90(4):1299-306.
PMID: 11247927
Chronic hypoxia causes pulmonary hypertension and right ventricular hypertrophy associated with pulmonary vascular remodeling. Because hypoxia might promote generation of oxidative stress in vivo, we hypothesized that oxidative stress may...