Myriam Duckely
Overview
Explore the profile of Myriam Duckely including associated specialties, affiliations and a list of published articles.
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9
Citations
97
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Recent Articles
1.
Meyer A, Baeschlin D, Brocklehurst C, Duckely M, Gallou F, Lovelle L, et al.
Chimia (Aarau)
. 2021 Nov;
75(11):936-942.
PMID: 34798915
We present a short overview of the way Novartis chemists interact and collaborate with the academic chemistry community in Switzerland. This article exemplifies a number of collaborations, and illustrates opportunities...
2.
Haffke M, Duckely M, Bergsdorf C, Jaakola V, Shrestha B
Protein Expr Purif
. 2019 Nov;
167:105545.
PMID: 31778786
The generation of integral membrane proteins (IMPs) in heterologous systems and their characterization remains a major challenge in biomedical research. Significant efforts have been invested both in academia and in...
3.
Haffke M, Fehlmann D, Rummel G, Boivineau J, Duckely M, Gommermann N, et al.
Nature
. 2019 Oct;
574(7779):581-585.
PMID: 31645725
The tricarboxylic acid cycle intermediate succinate is involved in metabolic processes and plays a crucial role in the homeostasis of mitochondrial reactive oxygen species. The receptor responsible for succinate signalling,...
4.
Bergsdorf C, Fiez-Vandal C, Sykes D, Bernet P, Aussenac S, Charlton S, et al.
J Biomol Screen
. 2015 Dec;
21(3):243-51.
PMID: 26644402
Integral membrane proteins (IMPs) play an important role in many cellular events and are involved in numerous pathological processes. Therefore, understanding the structure and function of IMPs is a crucial...
5.
Fiez-Vandal C, Leder L, Freuler F, Sykes D, Charlton S, Siehler S, et al.
Biophys Chem
. 2012 May;
165-166:56-61.
PMID: 22542136
To broaden the use of the recombinant high-density lipoprotein (rHDL) approach to the characterization of lead compounds, we investigated the pharmacology of the human beta-2-adrenoceptor in nanolipid bilayers (rHDL) with...
6.
Grange W, Duckely M, Husale S, Jacob S, Engel A, Hegner M
PLoS Biol
. 2008 Feb;
6(2):e44.
PMID: 18303950
The translocation of single-stranded DNA (ssDNA) across membranes of two cells is a fundamental biological process occurring in both bacterial conjugation and Agrobacterium pathogenesis. Whereas bacterial conjugation spreads antibiotic resistance,...
7.
Eifler N, Duckely M, Sumanovski L, Egan T, Oksche A, Konopka J, et al.
J Struct Biol
. 2007 Mar;
159(2):179-93.
PMID: 17368047
In native tissues, the majority of medically important membrane proteins is only present at low concentrations, making their overexpression in recombinant systems a prerequisite for structural studies. Here, we explore...
8.
Duckely M, Oomen C, Axthelm F, Van Gelder P, Waksman G, Engel A
Mol Microbiol
. 2005 Nov;
58(4):1130-42.
PMID: 16262795
The VirE2 protein is crucial for the transfer of single-stranded DNA (ssDNA) from Agrobacterium tumefaciens to the nucleus of the plant host cell because of its ssDNA binding activity, assistance...
9.
Duckely M, Hohn B
FEMS Microbiol Lett
. 2003 Jun;
223(1):1-6.
PMID: 12798992
Agrobacterium tumefaciens has evolved a unique mechanism to solve the problem of transferring DNA across five bilayers; the inner and outer membranes of the bacterium, the plasma membrane of the...