Myriam Bennoun
Overview
Explore the profile of Myriam Bennoun including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
896
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Recent Articles
1.
Lesbordes-Brion J, Viatte L, Bennoun M, Lou D, Ramey G, Houbron C, et al.
Blood
. 2006 Apr;
108(4):1402-5.
PMID: 16574947
We previously reported that mice made deficient for the transcriptional factor USF2 fail to express hepcidin 1 and hepcidin 2 genes as a consequence of targeted disruption of the Usf2...
2.
Viatte L, Nicolas G, Lou D, Bennoun M, Lesbordes-Brion J, Canonne-Hergaux F, et al.
Blood
. 2005 Dec;
107(7):2952-8.
PMID: 16339398
We report the generation of a tetracycline-regulated (Tet ON) transgenic mouse model for acute and chronic expression of the iron regulatory peptide hepcidin in the liver. We demonstrate that short-term...
3.
Lou D, Molina T, Bennoun M, Porteu A, Briand P, Joulin V, et al.
Cancer Lett
. 2005 Sep;
229(1):107-14.
PMID: 16157222
We closely mimicked the in vivo setting in which sporadic hepatocarcinoma occurs by establishing a transgenic mouse model carrying regulatable SV40 early sequences under the control of the regulatory sequences...
4.
Lou D, Lesbordes J, Nicolas G, Viatte L, Bennoun M, van Rooijen N, et al.
Hepatology
. 2005 Mar;
41(5):1056-64.
PMID: 15793843
Hepcidin, a recently discovered iron regulatory peptide, is believed to inhibit the release of iron from absorptive enterocytes and macrophages. Liver hepcidin synthesis is induced in vivo by iron stores...
5.
Viatte L, Lesbordes-Brion J, Lou D, Bennoun M, Nicolas G, Kahn A, et al.
Blood
. 2005 Feb;
105(12):4861-4.
PMID: 15713792
Evidence is accumulating that hepcidin, a liver regulatory peptide, could be the common pathogenetic denominator of all forms of iron overload syndromes including HFE-related hemochromatosis, the most prevalent genetic disorder...
6.
Nicolas G, Viatte L, Lou D, Bennoun M, Beaumont C, Kahn A, et al.
Nat Genet
. 2003 Apr;
34(1):97-101.
PMID: 12704388
Hereditary hemochromatosis is a prevalent genetic disorder of iron hyperabsorption leading to hyperferremia, tissue iron deposition and complications including cirrhosis, hepatocarcinoma, cardiomyopathy and diabetes. Most individuals affected with hereditary hemochromatosis...
7.
Nicolas G, Viatte L, Bennoun M, Beaumont C, Kahn A, Vaulont S
Blood Cells Mol Dis
. 2003 Jan;
29(3):327-35.
PMID: 12547223
Maintaining normal iron homeostasis is essential for the organism, as both iron deficiency and iron excess are associated with cellular dysfunction. Recently, several lines of evidence have suggested that hepcidin,...
8.
Viollet B, Andreelli F, Jorgensen S, Perrin C, Geloen A, Flamez D, et al.
J Clin Invest
. 2003 Jan;
111(1):91-8.
PMID: 12511592
AMP-activated protein kinase (AMPK) is viewed as a fuel sensor for glucose and lipid metabolism. To better understand the physiological role of AMPK, we generated a knockout mouse model in...
9.
Zhang P, Bennoun M, Gogard C, Bossard P, Leclerc I, Kahn A, et al.
Mech Dev
. 2002 Oct;
119(1):109-14.
PMID: 12385758
In mammals, the COUP-TF-family consisting of two structurally related proteins, COUP-TFI and COUP-TFII belongs to the orphan member of the steroid/thyroid hormone receptor superfamily. In an attempt to gain insights...
10.
Nicolas G, Bennoun M, Porteu A, Mativet S, Beaumont C, Grandchamp B, et al.
Proc Natl Acad Sci U S A
. 2002 Apr;
99(7):4596-601.
PMID: 11930010
We recently reported the hemochromatosis-like phenotype observed in our Usf2 knockout mice. In these mice, as in murine models of hemochromatosis and patients with hereditary hemochromatosis, iron accumulates in parenchymal...