Myeong-Kyun Shin
Overview
Explore the profile of Myeong-Kyun Shin including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
239
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0
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Recent Articles
1.
Gunder L, Blaine-Sauer S, Johnson H, Shin M, Auyeung A, Zhang W, et al.
Viruses
. 2022 Jul;
14(8).
PMID: 35893697
The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated...
2.
Blaine-Sauer S, Shin M, Matkowskyj K, Ward-Shaw E, Lambert P
mBio
. 2021 Jul;
12(4):e0161121.
PMID: 34281391
Up to 95% of all anal cancers are associated with infection by human papillomavirus (HPV); however, no established preclinical model exists for high-grade anal disease and cancer mediated by a...
3.
Shin M, Payne S, Bilger A, Matkowskyj K, Carchman E, Meyer D, et al.
Clin Cancer Res
. 2018 Dec;
25(6):1889-1900.
PMID: 30530704
Purpose: Over 95% of human anal cancers are etiologically associated with high-risk HPVs, with HPV type 16 (HPV16) the genotype most commonly found. Activating mutations in the catalytic subunit of...
4.
Park J, Shin M, Pitot H, Lambert P
PLoS One
. 2013 Oct;
8(9):e75056.
PMID: 24086435
Fanconi anemia (FA) patients are highly susceptible to solid tumors at multiple anatomical sites including head and neck region. A subset of head and neck cancers (HNCs) is associated with...
5.
Shin M, Sage J, Lambert P
Cancer Res
. 2012 Sep;
72(20):5418-27.
PMID: 22942253
Human papillomavirus-16 (HPV-16) is associated etiologically with many human cervical cancers. It encodes 3 oncogenes E5, E6, and E7. Of these oncogenes, E7 has been found to be the dominant...
6.
Shin M, Pitot H, Lambert P
Cancer Res
. 2012 Jan;
72(5):1280-9.
PMID: 22237625
Head and neck squamous cell carcinomas (HNSCC) is a common cancer in humans long known to be caused by tobacco and alcohol use, but now an increasing percentage of HNSCC...
7.
Lee J, Shin M, Ryu D, Kim S, Ryu W
Methods Mol Biol
. 2010 Aug;
634:137-46.
PMID: 20676981
Mutagenesis by the overlap extension PCR has become a standard method of creating mutations including substitutions, insertions, and deletions. Nonetheless, the established overlap PCR mutagenesis is limited in many respects....
8.
Shin M, Balsitis S, Brake T, Lambert P
Cancer Res
. 2009 Jul;
69(14):5656-63.
PMID: 19584294
The E7 oncoprotein of the high-risk human papillomaviruses (HPV) is thought to contribute to cervical carcinogenesis at least in part by abrogating cell cycle regulation. E7 can dysregulate the cell...
9.
Lee H, Lee J, Shin M, Ryu W
Mol Cells
. 2008 May;
25(4):545-52.
PMID: 18460902
A hepadnaviruses replicates its DNA genome via reverse transcription of an RNA template (pregenomic RNA or pgRNA), which has a cap structure at the 5' end and a poly(A) tail...
10.
Shin M, Kim J, Ryu D, Ryu W
Virology
. 2007 Nov;
371(2):362-73.
PMID: 17988705
Although an overall genetic strategy for hepadnaviral reverse transcription has been established, the mechanism that underlies the minus-strand transfer is still poorly defined. We and others independently identified a novel...