Muzhou Jiang
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Explore the profile of Muzhou Jiang including associated specialties, affiliations and a list of published articles.
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12
Citations
88
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Recent Articles
1.
Jiang M, Ge Z, Yin S, Liu Y, Gao H, Lu L, et al.
J Clin Periodontol
. 2024 Dec;
52(3):434-456.
PMID: 39726227
Aim: Porphyromonas gingivalis , a consensus periodontal pathogen, is thought to be involved in Alzheimer's disease (AD) progression, and P. gingivalis -derived outer membrane vesicles (PgOMVs) are a key toxic...
2.
Jiang M, Zhao D, Zhou Y, Kong W, Xie Z, Xiong Y, et al.
Neuropsychopharmacology
. 2024 Sep;
50(4):640-650.
PMID: 39304744
The approval of anti-amyloid β (Aβ) monoclonal antibodies (lecanemab) for the treatment of patients with early preclinical stage of Alzheimer's disease (AD) by the Food and Drug Administration, suggests the...
3.
Zhao S, Jiang M, Qing H, Ni J
Br J Pharmacol
. 2023 Jul;
180(19):2455-2481.
PMID: 37403614
Coronavirus disease-19 (COVID-19) is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. The COVID-19 pandemic began in March 2020 and has wrought havoc on health and economic systems worldwide. Efficacious...
4.
Wang Y, Zhao J, Gu Y, Wang H, Jiang M, Zhao S, et al.
Biochem Pharmacol
. 2023 May;
212:115585.
PMID: 37148981
Cathepsin H (CatH) is a lysosomal cysteine protease with a unique aminopeptidase activity that is extensively expressed in the lung, pancreas, thymus, kidney, liver, skin, and brain. Owing to its...
5.
Zhang S, Meng R, Jiang M, Qing H, Ni J
Curr Neuropharmacol
. 2023 Feb;
22(7):1189-1204.
PMID: 36740799
The blood-brain barrier (BBB) is a highly selective interface between the blood and the brain parenchyma. It plays an essential role in maintaining a specialized environment for central nervous system...
6.
Wang H, Peng W, Zhang G, Jiang M, Zhao J, Zhao X, et al.
Eur J Oral Sci
. 2022 Jan;
130(2):e12851.
PMID: 35049069
Porphyromonas gingivalis is the main pathogen of chronic periodontitis. However, the specific mechanisms through which P. gingivalis induces immune and inflammatory responses in periodontitis have not been completely elucidated. In...
7.
Jiang M, Zhang X, Yan X, Mizutani S, Kashiwazaki H, Ni J, et al.
Brain Behav Immun
. 2021 Aug;
98:1-12.
PMID: 34391814
In line with the strong association between periodontitis and Alzheimer's disease (AD) clinically, preclinical studies have shown that systemic exposure to Porphyromonas gingivalis (Pg) initiates AD pathologies. However, the involvement...
8.
Huang W, Zeng F, Gu Y, Jiang M, Zhang X, Yan X, et al.
J Alzheimers Dis
. 2021 Aug;
83(2):665-681.
PMID: 34334391
Background: Studies have reported that synaptic failure occurs before the Alzheimer's disease (AD) onset. The systemic Porphyromonas gingivalis (P. gingivalis) infection is involved in memory decline. We previously showed that...
9.
Ishiguro S, Shinada T, Wu Z, Karimazawa M, Uchidate M, Nishimura E, et al.
PLoS One
. 2021 Jan;
16(1):e0245235.
PMID: 33503058
The use of agents that target both glia and neurons may represent a new strategy for the treatment of ageing disorders. Here, we confirmed the presence of the novel cyclic...
10.
Gu Y, Wu Z, Zeng F, Jiang M, Teeling J, Ni J, et al.
J Alzheimers Dis
. 2020 Sep;
78(1):61-74.
PMID: 32925065
Background: Alzheimer's disease (AD) and bone loss are clinically exacerbated. However, the mechanism of exacerbation remains understood. Objective: We tested our hypothesis that periodontitis is involved in the exacerbation, contributing...