Murat Tekguc
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Explore the profile of Murat Tekguc including associated specialties, affiliations and a list of published articles.
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8
Citations
267
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Recent Articles
1.
Borges T, Ganchiku Y, Aceves J, van Gaal R, Uzel S, Rosales I, et al.
iScience
. 2024 Oct;
27(10):110957.
PMID: 39398250
The increasing scarcity of organs and the significant morbidity linked to dialysis require the development of engineered kidney tissues from human-induced pluripotent stem cells. Integrative approaches that synergize scalable kidney...
2.
Yoon S, Meyer M, Arevalo C, Tekguc M, Zhang C, Wang J, et al.
J Clin Invest
. 2023 Mar;
133(9).
PMID: 36862513
The renal actions of parathyroid hormone (PTH) promote 1,25-vitamin D generation; however, the signaling mechanisms that control PTH-dependent vitamin D activation remain unknown. Here, we demonstrated that salt-inducible kinases (SIKs)...
3.
Tekguc M, Gaal R, Uzel S, Gupta N, Riella L, Lewis J, et al.
Transl Res
. 2022 Jun;
250:1-17.
PMID: 35750295
The kidney is a vital organ that regulates the bodily fluid and electrolyte homeostasis via tailored urinary excretion. Kidney injuries that cause severe or progressive chronic kidney disease have driven...
4.
Nyati K, Hashimoto S, Singh S, Tekguc M, Metwally H, Liu Y, et al.
Cancer Lett
. 2021 Aug;
520:295-306.
PMID: 34389433
Interleukin (IL-6) is a pleotropic cytokine with both tumor-promoting and -inhibitory effects on breast cancer growth. However, the mechanisms governing the outcome of IL-6 on cancer progression remain to be...
5.
Tekguc M, Wing J, Osaki M, Long J, Sakaguchi S
Proc Natl Acad Sci U S A
. 2021 Jul;
118(30).
PMID: 34301886
Foxp3-expressing CD4CD25 regulatory T cells (Tregs) constitutively and highly express the immune checkpoint receptor cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), whose Treg-specific deficiency causes severe systemic autoimmunity. As a key mechanism of...
6.
Parajuli G, Tekguc M, Wing J, Hashimoto A, Okuzaki D, Hirata T, et al.
Cancer Immunol Res
. 2021 May;
9(8):862-876.
PMID: 34006522
The acquisition of mesenchymal traits leads to immune evasion in various cancers, but the underlying molecular mechanisms remain unclear. In this study, we found that the expression levels of AT-rich...
7.
Wing J, Tekguc M, Sakaguchi S
Front Immunol
. 2018 Sep;
9:1910.
PMID: 30197643
Regulatory T-cells (Treg cells), expressing the transcription factor Foxp3, have an essential role in the control of immune homeostasis. In order to control diverse types of immune responses Treg cells...
8.
Yalvac M, Ramazanoglu M, Tekguc M, Bayrak O, Shafigullina A, Salafutdinov I, et al.
Curr Neurovasc Res
. 2010 Feb;
7(1):49-58.
PMID: 20158462
The use of mesenchymal stem cells (MSCs) has been shown to be promising in chronic disorders such as diabetes, Alzheimer's dementia, Parkinson's disease, spinal cord injury and brain ischemia. Recent...