Mubeen A Ansari
Overview
Explore the profile of Mubeen A Ansari including associated specialties, affiliations and a list of published articles.
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22
Citations
1039
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Recent Articles
1.
Yadikar H, Ansari M, Abu-Farha M, Joseph S, Thomas B, Al-Mulla F
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928172
Alzheimer's disease (AD), the leading cause of dementia worldwide, remains a challenge due to its complex origin and degenerative character. The need for accurate biomarkers and treatment targets hinders early...
2.
Ansari M, Al-Jarallah A, Rao M, Babiker A, Bensalamah K
Brain Res
. 2024 Mar;
1834:148890.
PMID: 38552936
NADPH-oxidase (NOX) is a multi-subunit enzyme complex. The upregulation of NOX causes massive production of superoxide (O), which avidly reacts with nitric oxide (NO) and increases cellular reactive oxygen/nitrogen species...
3.
Ansari M, Rao M, Al-Jarallah A
Front Neurosci
. 2024 Jan;
17:1273626.
PMID: 38260013
Oxidative stress, induced by impaired insulin signaling in the brain contributes to cognitive loss in sporadic Alzheimer's disease (sAD). This study evaluated early hippocampal oxidative stress, pre- and post-synaptic proteins...
4.
Ansari M, Al-Jarallah A, Babiker F
Cells
. 2023 Jul;
12(13).
PMID: 37443762
Alzheimer's disease (AD) is a neurological condition that affects the elderly and is characterized by progressive and irreversible neurodegeneration in the cerebral cortex [...].
5.
Ansari M, Rao M, Al-Jarallah A, Babiker F
Brain Res
. 2022 Nov;
1798:148134.
PMID: 36328067
Oxidative stress, caused by impaired insulin signaling, plays a pivotal role in the pathogenesis of sporadic Alzheimer's disease (sAD). We investigated the oxidative stress parameters in the synaptosomes prepared from...
6.
Scheff S, Ansari M
J Neurotrauma
. 2016 Nov;
34(8):1491-1510.
PMID: 27846772
There has been a tremendous focus on the discovery and development of neuroprotective agents that might have clinical relevance following traumatic brain injury (TBI). This type of brain injury is...
7.
Scheff S, Ansari M, Mufson E
Neurobiol Aging
. 2016 May;
42:1-12.
PMID: 27143416
Neuritic amyloid plaques and neurofibrillary tangles are hallmarks of Alzheimer's disease (AD) and are major components used for the clinical diagnosis of this disorder. However, many individuals with no cognitive...
8.
Ansari M
J Neurol Sci
. 2015 Jul;
357(1-2):41-9.
PMID: 26148932
Traumatic brain injury (TBI) elicits complex inflammatory assets (M1 and M2 responses) in the brain that include the expression of various cytokines/chemokines and the recruitment of blood cells, contributing secondary...
9.
Ansari M, Roberts K, Scheff S
Free Radic Biol Med
. 2014 Sep;
77:21-9.
PMID: 25224032
Nicotinamide adenine dinucleotide phosphate oxidase (NADPH-oxidase; NOX) is a complex enzyme responsible for increased levels of reactive oxygen species (ROS), superoxide (O2(•-)). NOX-derived O2(•-) is a key player in oxidative...
10.
Scheff S, Price D, Ansari M, Roberts K, Schmitt F, Ikonomovic M, et al.
J Alzheimers Dis
. 2014 Aug;
43(3):1073-90.
PMID: 25147118
Mild cognitive impairment (MCI) is considered to be an early stage in the progression of Alzheimer's disease (AD) providing an opportunity to investigate brain pathogenesis prior to the onset of...