Motomi Konishi
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Explore the profile of Motomi Konishi including associated specialties, affiliations and a list of published articles.
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20
Citations
92
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Recent Articles
11.
Taniguchi M, Matsuura K, Nakamura R, Kojima A, Konishi M, Akizawa T
Biometals
. 2017 Sep;
30(5):797-807.
PMID: 28871443
The extracellular deposition of amyloid β (Aβ) is known to be the fundamental cause of Alzheimer's disease (AD). Aβ1-42, generated by β-secretases from the amyloid precursor protein (APP), is the...
12.
Yasuno Y, Hamada M, Yoshida Y, Shimamoto K, Shigeri Y, Akizawa T, et al.
Bioorg Med Chem Lett
. 2016 Jun;
26(15):3543-6.
PMID: 27329796
Kaitocephalin (KCP) isolated from Eupenicillium shearii PF1191 is an unusual amino acid natural product in which serine, proline, and alanine moieties are liked with carbon-carbon bonds. KCP exhibits potent and...
13.
Yasuno Y, Hamada M, Kawasaki M, Shimamoto K, Shigeri Y, Akizawa T, et al.
Org Biomol Chem
. 2015 Dec;
14(4):1206-10.
PMID: 26660454
A structure-activity relationship (SAR) study of kaitocephalin (KCP), known to be a potent naturally occurring NMDA receptor ligand, was performed. This study led us to the discovery of (7S)-kaitocephalin as...
14.
Yasuhara T, Sone T, Konishi M, Kushihata T, Nishikawa T, Yamamoto Y, et al.
Yakugaku Zasshi
. 2015 May;
135(5):753-9.
PMID: 25948313
The KJ method (named for developer Jiro Kawakita; also known as affinity diagramming) is widely used in participatory learning as a means to collect and organize information. In addition, the...
15.
Kurio W, Konishi M, Okuno T, Nakao T, Kimura T, Tsuji T, et al.
Yakugaku Zasshi
. 2014 Nov;
134(11):1199-208.
PMID: 25366917
The Faculty of Pharmaceutical Sciences, Setsunan University, offers the Self-improvement and Participatory Career Development Education Program: Internship and Volunteer Training Experience for Pharmacy Students to third-year students. We previously reported...
16.
Kojima A, Konishi M, Akizawa T
Biomolecules
. 2014 Jun;
4(2):510-26.
PMID: 24970228
Prions are the cause of neurodegenerative disease in humans and other mammals. The structural conversion of the prion protein (PrP) from a normal cellular protein (PrPC) to a protease-resistant isoform...
17.
Yasuhara T, Konishi M, Nishida T, Kushihata T, Sone T, Kurio W, et al.
Yakugaku Zasshi
. 2014 Feb;
134(2):185-94.
PMID: 24492221
Learning chemistry is cumulative: basic knowledge and chemical calculation skills are required to gain understanding of higher content. However, we often suffer from students' lack of learning skills to acquire...
18.
Kojima A, Mabuchi Y, Konishi M, Okihara R, Nagano M, Akizawa T
Chem Pharm Bull (Tokyo)
. 2011 Aug;
59(8):965-71.
PMID: 21804240
The structural conversion of the prion protein (PrP) from the normal cellular isoform (PrP(C)) to the posttranslationally modified form (PrP(Sc)) is thought to relate to Cu²⁺ binding to histidine (H)...
19.
Aihara Y, Yoshida A, Furuta T, Wakimoto T, Akizawa T, Konishi M, et al.
Bioorg Med Chem Lett
. 2009 Jun;
19(15):4171-4.
PMID: 19524436
Regioselective synthesis of methylated epigallocatechin gallate from epigallocatechin was accomplished using a 2-nitrobenzenesulfonyl (Ns) group as a protecting group for phenols. This methodology provided several methylated catechins, which are naturally...
20.
Yoshika M, Komiyama Y, Konishi M, Akizawa T, Kobayashi T, Date M, et al.
Hypertension
. 2006 Nov;
49(1):209-14.
PMID: 17116763
Marinobufagenin and telecinobufagin have been identified as digitalis-like factors in mammals. In toads, marinobufagenin-related compounds, such as marinobufotoxin (MBT), have been isolated in some tissues but not in mammals, and...